Deep Eutectic Solvents to Organic Synthesis

Deep eutectic solvents ( DES) is a new type of environmentally green solvents. Compared with conventional organic solvents, DES have more advantages, such as negligible vapor pressure, non-flammability, good chemical and thermal stability, non-toxicity, biodegradability, recyclability and low price among others. As a new type of solvent, DES has an extremely extensive application prospect. The latest research results of DES is reviewed in this paper. DES as a novel solvent and catalyst was applied in the traditional organic synthesis reaction, mainly including Helogenation reaction, Diels-Alder reaction, Knoevenagel reaction, Henry reaction, Perkin reaction, Paal-Knorr reaction, Biginelli reaction. At last, we hope that DES has a good application prospect in the field of organic synthesis.