Validation of a leg movements count and periodic leg movements analysis in a custom polysomnography system

被引:29
作者
Stefani, Ambra [1 ]
Heidbreder, Anna [1 ]
Hackner, Heinz [1 ]
Hoegl, Birgit [1 ]
机构
[1] Med Univ Innsbruck, Dept Neurol, Anichstr 35, A-6020 Innsbruck, Austria
关键词
PLM; Restless legs syndrome; Sleep; PSG; Computerized scoring; SLEEP; CRITERIA; ATROPHY; PLM;
D O I
10.1186/s12883-017-0821-6
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background: Periodic leg movements (PLM) during sleep (PLMS) are considered strongly related to restless legs syndrome (RLS), and are associated with polymorphisms in RLS risk genes. Various software for automatic analysis of PLMS are available, but only few of them have been validated. Aim of this study was to validate a leg movements count and analysis integrated in a commercially available polysomnography (PSG) system against manual scoring. Methods: Twenty RLS patients with a PLMS index > 20/h and 20 controls with a PLMS index < 5/h were included. Manual and computerized scoring of leg movements (LM) and PLM was performed according to the standard American Academy of Sleep Medicine (AASM) criteria. LM and PLM indices during sleep and wakefulness, the rate of PLMS associated with respiratory events, intermovement interval and periodicity indices were manually and automatically scored. Results: The correlation between manual and computerized scoring was high for all investigated parameters (Spearman correlation coefficients 0.751-0.996, p < 0.001; intraclass correlation coefficients 0.775-0.999, p < 0.001). Bland-Altman plots showed high agreement between manual and automatic analysis. Conclusions: This study validated an automatic LM count and PLM analysis against the gold standard manual scoring according to AASM criteria. The data demonstrate that the software used in this study has an outstanding performance for computerized LM and PLM scoring, and LM and PLM indices generated with this software can be reliably integrated in the routine PSG report. This automatic analysis is also an excellent tool for research purposes.
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页数:9
相关论文
共 21 条
[1]   Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology - A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health [J].
Allen, RP ;
Picchietti, D ;
Hening, WA ;
Trenkwalder, C ;
Walters, AS ;
Montplaisi, J .
SLEEP MEDICINE, 2003, 4 (02) :101-119
[2]   SLEEP-APNEA AND PERIODIC MOVEMENTS IN AN AGING SAMPLE [J].
ANCOLIISRAEL, S ;
KRIPKE, DF ;
MASON, W ;
KAPLAN, OJ .
JOURNALS OF GERONTOLOGY, 1985, 40 (04) :419-425
[3]   COMPARATIVE POLYSOMNOGRAPHIC STUDY OF NARCOLEPSY AND IDIOPATHIC CENTRAL-NERVOUS-SYSTEM HYPERSOMNIA [J].
BAKER, TL ;
GUILLEMINAULT, C ;
NINOMURCIA, G ;
DEMENT, WC .
SLEEP, 1986, 9 (01) :232-242
[4]  
Berry R., 2017, The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications
[5]   Periodic leg movements in REM sleep behavior disorder and related autonomic and EEG activation [J].
Fantini, ML ;
Michaud, M ;
Gosselin, N ;
Lavigne, G ;
Montplaisir, J .
NEUROLOGY, 2002, 59 (12) :1889-1894
[6]   Computer-assisted detection of nocturnal leg motor activity in patients with restless legs syndrome and periodic leg movements during sleep [J].
Ferri, R ;
Zucconi, M ;
Manconi, M ;
Bruni, O ;
Miano, S ;
Plazzi, G ;
Ferini-Strambi, L .
SLEEP, 2005, 28 (08) :998-1004
[7]  
Ferri R, 2006, SLEEP, V29, P759
[8]   Motor Events during Healthy Sleep: A Quantitative Polysomnographic Study [J].
Frauscher, Birgit ;
Gabelia, David ;
Mitterling, Thomas ;
Biermayr, Marlene ;
Bregler, Deborah ;
Ehrmann, Laura ;
Ulmer, Hanno ;
Hoegl, Birgit .
SLEEP, 2014, 37 (04) :763-U367
[9]   Periodic limb movement counting in polysomnography:: Effects of amplitude [J].
Gschliesser, Viola ;
Brandauer, Elisabeth ;
Ulmer, Hanno ;
Poewe, Werner ;
Hoegl, Birgit .
SLEEP MEDICINE, 2006, 7 (03) :249-254
[10]   PLM detection by actigraphy compared to polysomnography: A validation and comparison of two actigraphs [J].
Gschliesser, Viola ;
Frauscher, Birgit ;
Brandauer, Elisabeth ;
Kohnen, Ralf ;
Ulmer, Hanno ;
Poewe, Werner ;
Hoegl, Birgit .
SLEEP MEDICINE, 2009, 10 (03) :306-311