Synthesis and antibacterial activities of pyrano[3,2-b]pyranones from kojic acid, ethyl cyanoacetate, and benzaldehydes in aqueous K2CO3

被引：26

作者：

Asghari, Sakineh ^{[1
,2
]}

Baharfar, Robabeh ^{[2
]}

Alimi, Manag ^{[2
]}

Ahmadipour, Mohammad ^{[2
]}

Mohseni, Mojtaba ^{[3
]}

机构：

[1] Univ Mazandaran, Nano & Biotechnol Res Grp, Babol Sar, Iran

[2] Univ Mazandaran, Fac Chem, Dept Organ Chem, Babol Sar 4741695447, Iran

[3] Univ Mazandaran, Dept Biol, Babol Sar, Iran

来源：

MONATSHEFTE FUR CHEMIE | 2014年 / 145卷 / 08期

关键词：

Green chemistry; Three-component reaction; Kojic acid; Benzaldehydes; Michael addition; Antibacterial activities; ONE-POT SYNTHESIS; 3-COMPONENT SYNTHESIS; EFFICIENT; CONVENIENT; CATALYST; PYRAN;

D O I：

10.1007/s00706-014-1190-0

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Pyrano[3,2-b]pyranones are prepared in good yields from three-component coupling of kojic acid, ethyl cyanoacetate, and benzaldehydes in aqueous K2CO3. The synthetic compounds exert moderate activity against both Gram positive and Gram negative bacteria and their effectiveness is higher against Bacillus subtilis.

引用

页码：1337 / 1342

页数：6

共 30 条

[1]

Anastas P., 1998, Green Chemistry: Theory and Practice

[2]

Anastas PT, 1998, GREEN CHEMISTRY, P1

[3] SYNTHESIS OF CYCLOBUTENES BY THE NOVEL PHOTOCHEMICAL RING CONTRACTION OF 4-SUBSTITUTED 2-AMINO-3,5-DICYANO-6-PHENYL-4H-PYRANS [J].