Transgenic UDP-glucuronosyltransferase 1 (Tg-UGT1) mice are protected from obesity-induced type 2 diabetes

被引：0
|
作者：
Bonzo, Jessica [1 ]
Senekeo-Effenberger, Kathy [1 ]
Tukey, Robert [1 ]
机构：
[1] Univ Calif San Diego, La Jolla, CA 92093 USA
来源：
ACTA PHARMACOLOGICA SINICA | 2006年 / 27卷
关键词：
transgenic mice; UGT1A; diabetes; glucuronidation;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
引用
收藏
页码：307 / 307
页数：1
相关论文
共 50 条
  • [21] Glucuronidation of icaritin by human liver microsomes, human intestine microsomes and expressed UDP-glucuronosyltransferase enzymes: identification of UGT1A3, 1A9 and 2B7 as the main contributing enzymes
    Wang, Li
    Hong, Xiaodan
    Yao, Zhihong
    Dai, Yi
    Zhao, Guoping
    Qin, Zifei
    Wu, Baojian
    Gonzalez, Frank J.
    Yao, Xinsheng
    XENOBIOTICA, 2018, 48 (04) : 357 - 367
  • [22] Fatty Liver/Adipose Tissue Dual-Targeting Nanoparticles with Heme Oxygenase-1 Inducer for Amelioration of Obesity, Obesity-Induced Type 2 Diabetes, and Steatohepatitis
    Hong, Juhyeong
    Kim, Yong-Hee
    ADVANCED SCIENCE, 2022, 9 (33)
  • [23] Glutathione peroxidase-1 overexpressing transgenic mice are protected from cocaine-induced drug dependence
    Mai, Huynh Nhu
    Chung, Yoon Hee
    Shin, Eun-Joo
    Kim, Dae-Joong
    Sharma, Naveen
    Lee, Yu Jeung
    Jeong, Ji Hoon
    Nah, Seung-Yeol
    Jang, Choon-Gon
    Kim, Hyoung-Chun
    NEUROCHEMISTRY INTERNATIONAL, 2019, 124 : 264 - 273
  • [24] UDP-glucuronosyltransferase 1A4-mediated N2-glucuronidation is the major metabolic pathway of lamotrigine in chimeric NOG-TKm30 mice with humanised-livers
    Uehara, Shotaro
    Higuchi, Yuichiro
    Yoneda, Nao
    Yamazaki, Hiroshi
    Suemizu, Hiroshi
    XENOBIOTICA, 2021, 51 (10) : 1146 - 1154
  • [25] Effects of captopril on glucose metabolism and autophagy in liver and muscle from mice with type 1 diabetes and diet-induced obesity
    Guimaraes, Joao Pedro Torres
    Menikdiwela, Kalhara R.
    Ramalho, Theresa
    Queiroz, Luiz A. D.
    Kalupahana, Nishan S.
    Jancar, Sonia
    Ramalingam, Latha
    Martins, Joilson O.
    Moustaid-Moussa, Naima
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2022, 1868 (10):
  • [26] 1H, 13C and 15N chemical shift assignments of the C-terminal domain of human UDP-Glucuronosyltransferase 2B7 (UGT2B7-C)
    Michael J. Osborne
    Amanda K. Rahardjo
    Laurent Volpon
    Katherine L. B. Borden
    Biomolecular NMR Assignments, 2021, 15 : 323 - 328
  • [27] 1H, 13C and 15N chemical shift assignments of the C-terminal domain of human UDP-Glucuronosyltransferase 2B7 (UGT2B7-C)
    Osborne, Michael J.
    Rahardjo, Amanda K.
    Volpon, Laurent
    Borden, Katherine L. B.
    BIOMOLECULAR NMR ASSIGNMENTS, 2021, 15 (02) : 323 - 328
  • [28] 1H, 13C, 15N Backbone and sidechain chemical shift assignments of the C-terminal domain of human UDP-glucuronosyltransferase 2B17 (UGT2B17-C)
    Anamika Sulekha
    Michael J. Osborne
    Jadwiga Gasiorek
    Katherine L. B. Borden
    Biomolecular NMR Assignments, 2023, 17 : 67 - 73
  • [29] 1H, 13C, 15N Backbone and sidechain chemical shift assignments of the C-terminal domain of human UDP-glucuronosyltransferase 2B17 (UGT2B17-C)
    Sulekha, Anamika
    Osborne, Michael J.
    Gasiorek, Jadwiga
    Borden, Katherine L. B.
    BIOMOLECULAR NMR ASSIGNMENTS, 2023, 17 (01) : 67 - 73
  • [30] Differences in the mechanism of type 1 and type 2 diabetes-induced skin dryness by using model mice
    Horikawa, Tsuneki
    Hiramoto, Keiichi
    Goto, Kenji
    Sekijima, Hidehisa
    Ooi, Kazuya
    INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2021, 18 (02): : 474 - 481
12345