Glochidiolide, isoglochidiolide, acuminaminoside, and glochidacuminosides A-D from the leaves of Glochidion acuminatum MUELL.

被引:17
作者
Otsuka, H
Takeda, Y
Hirata, E
Shinzato, T
Bando, M
机构
[1] Hiroshima Univ, Grad Sch Biomed Sci, Dept Pharmacognosy, Minami Ku, Hiroshima 7348551, Japan
[2] Univ Tokushima, Fac Integrated Arts & Sci, Tokushima 7708502, Japan
[3] Univ Ryukyus, Fac Agr, Okinawa 9030129, Japan
[4] Univ Ryukyus, Fac Agr, Subtrop Field Sci Ctr, Okinawa 9051427, Japan
[5] Otsuka Pharmaceut Co Ltd, Med Chem Res Inst, Tokushima 7708502, Japan
关键词
Glocludion acuminatum; Euphorbiaceae; dimeric phenylethane; alkaloidal glucoside; acuminaminoside; glochi-dacuminoside;
D O I
10.1248/cpb.52.591
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The dimeric butenolides glochidiolide and isoglochidiolide, a new glucoside of a nitrogen-containing C, dimer, acuminaminoside, and glucosides of C, compounds, designated glochidacuminosides A-D, were isolated from the leaves of Glochidion acuminatum. The structures of glochidionolactone and acuminaminoside were determined by X-ray analyses, and those of the remaining C-8 glucosides by NMR spectroscopic analyses, chemical conversion, and a modified Mosher's method.
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页码:591 / 596
页数:6
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