Synthesis and Antimicrobial Activity of 5-Imidazolinone Derivatives

被引：34

作者：

Desai, N. C. ^{[1
]}

Bhavsar, A. M. ^{[1
]}

Baldaniya, B. B. ^{[1
]}

机构：

[1] Bhavnagar Univ, Univ Dept Chem, Div Med Chem, Bhavnagar 364002, Gujarat, India

来源：

INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2009年 / 71卷 / 01期

关键词：

5-Imidazolinone; antibacterial activity; antifungal activity; ANTI-HIV AGENTS; ANTICANCER;

D O I：

10.4103/0250-474X.51953

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Several 4-arylidene-2-phenyl-1-(2,4,5-trichlorophenyl)-1H-imidazol-5(4H)-ones (4a-q), N-(4-benzylidene-5-oxo-2-phenyl-4,5-dihydroimidazol-1-yl)-4-chlorobenzamides (5a-o) and N-(4-benzylidene-5-oxo-2-phenyl-4,5-dihydroimidazol-1-yl)-2,4-dichlorobenzamides (6a-m) were prepared. All newly synthesized compounds have been tested for their antibacterial activity against gram (+)ve and gram (-)ve bacteria and also on different strains of fungi. Introduction of OH, OCH3, NO2, Cl and Br groups to the heterocyclic frame work enhanced antibacterial and antifungal activities.

引用

页码：90 / 94

页数：5

共 50 条

[1] 5-Imidazolinone Derivatives as a Potent Pharmacological Agents—A Review
B. Sivakumar
K. Ilango
Russian Journal of Bioorganic Chemistry, 2023, 49 : 167 - 179
[2] 5-Imidazolinone Derivatives as a Potent Pharmacological Agents-A Review
Sivakumar, B.
Ilango, K.
RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2023, 49 (02) : 167 - 179
[3] Syntheses and QSAR studies of 5-imidazolinone derivatives as potential antibacterial agents
Shah, MD
Desai, NC
Awasthi, KK
Saxena, AK
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2001, 40 (03): : 201 - 208
[4] Synthesis and antimicrobial activity of oxadiazole and imidazolinone derivatives bearing trimethoxybenzamide moiety
Joshi, N
Bapodra, A
Parekh, H
JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1996, 73 (12) : 700 - 701
[5] SYNTHESIS, CHARACTERIZATION AND ANTICONVULSANT ACTIVITY OF SUBSTITUTED IMIDAZOLINONE DERIVATIVES
Sudha, B. Naga
Subbaiah, N. Yella
Raghavendra, H. G.
Srikanth, A. M.
Reddy, C. Venkataramana
Manasa, A.
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2014, 24 (02) : 159 - 162
[6] Synthesis of imidazolinone and benzoxazole derivatives, and evaluation of their anticancer activity
Heba A. El-Hady
Samar A. Abubshait
Research on Chemical Intermediates, 2015, 41 : 1833 - 1841
[7] Synthesis of imidazolinone and benzoxazole derivatives, and evaluation of their anticancer activity
El-Hady, Heba A.
Abubshait, Samar A.
RESEARCH ON CHEMICAL INTERMEDIATES, 2015, 41 (03) : 1833 - 1841
[8] Synthesis and antimicrobial activity of 4-thiazolidinone and imidazolinone derivatives bearing 2-aminothiazole moiety
Patel, PH
Korgaokar, SS
Parekh, HH
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 1997, 7 (01) : 73 - 76
[9] Synthesis and antimicrobial activity of sulphonamide, imidazolinone, N,N'-(diaryldiamino)phosphinic chloride derivatives having ''Fluchloralin'' moiety
Purohit, DM
Shah, VH
HETEROCYCLIC COMMUNICATIONS, 1997, 3 (02) : 139 - 145
[10] Functional derivatives of 5-formylprotocatealdehyde - synthesis and antimicrobial activity
Nicolae, A
Stola, S
Maior, O
REVISTA DE CHIMIE, 1997, 48 (05): : 388 - 394

← 1 2 3 4 5 →