Motor signs distinguish children with high functioning autism and Asperger's syndrome from controls

被引:293
作者
Jansiewicz, Eva M.
Goldberg, Melissa C.
Newschaffer, Craig J.
Denckla, Martha B.
Landa, Rebecca
Mostofsky, Stewart H.
机构
[1] Johns Hopkins Univ, Sch Med, Kennedy Krieger Inst, Dept Neurol & Psychiat, Baltimore, MD 21218 USA
[2] Georgia State Univ, Atlanta, GA 30303 USA
[3] Johns Hopkins Univ, Sch Med, Dept Psychiat, Kennedy Krieger Inst, Baltimore, MD USA
[4] Johns Hopkins Univ, Sch Publ Hlth, Baltimore, MD USA
[5] Johns Hopkins Univ, Sch Med, Kennedy Krieger Inst, Dept Neurol, Baltimore, MD USA
[6] Johns Hopkins Univ, Sch Med, Kennedy Krieger Inst, Dept Pediat, Baltimore, MD USA
基金
美国国家卫生研究院;
关键词
coordination; dysrhythmia; overflow; gait; balance; motor speed;
D O I
10.1007/s10803-006-0109-y
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
While many studies of motor control in autism have focused on specific motor signs, there has been a lack of research examining the complete range of subtle neuromotor signs. This study compared performance on a neurologic examination standardized for children (PANESS, Physical and Neurological Exam for Subtle Signs, Denckla [1974 Developmental Medicine and Child Neurology, 16(6), 729-741]) between a group of 40 boys aged 6-17 with autism and average range IQs and a group of 55 typically developing boys. The Autism group was shown to have significant impairment on several measures of motor control compared to the Control group. Regression analyses revealed that a model including four PANESS variables offered a high level of discrimination in distinguishing boys with high-functioning autism from controls.
引用
收藏
页码:613 / 621
页数:9
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