Fabrication of pH-Responsive Molecularly Imprinted Polyethersulfone Particles for Bisphenol-A Uptake

被引：32

作者：

Zhao, W. F. ^{[1
]}

Fang, B. H. ^{[1
]}

Li, N. ^{[1
]}

Nie, S. Q. ^{[1
]}

Wei, Q. ^{[1
]}

Zhao, C. S. ^{[1
]}

机构：

[1] Sichuan Univ, Coll Polymer Sci & Engn, State Key Lab Polymer Mat Engn, Chengdu 610065, Peoples R China

来源：

JOURNAL OF APPLIED POLYMER SCIENCE | 2009年 / 113卷 / 02期

基金：

中国国家自然科学基金;

关键词：

pH-responsive; molecularly imprinted particle; polyethersulfone; bisphenol-A adsorption; SENSITIVE HYDROGEL; CONTROLLED-RELEASE; DRUG-DELIVERY; PERMEABILITY; SEPARATION; MEMBRANES; POLYMER; ALGINATE; BINDING;

D O I：

10.1002/app.30014

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

pH-responsive molecularly imprinted particles were successfully fabricated by pore-filling poly (acrylic acid) (PAA) gels into bisphenol-A (BPA)-imprinted poly-ethersulfone particles. The adsorbed BPA amount (or rate) decreased aftezr filling the PAA gels both for the imprinted and nonimprinted particles. However, it was confirmed that changing the acidity of the solution reversibly controls the rebinding ability toward BPA and that the BPA uptake of the pore-filled particles exhibited chemical valve behavior at a pH between 3 and 6. This finding can be attributed to the swelling of the PAA gels in the particles. The present methodology provides a simple way to prepare pH-responsive molecularly imprinted materials and is expandable to the imprinting of other hydrophobic molecules, such as dibenzofuran. Also, the results of this work demonstrate the potential of stimuli-responsive molecularly imprinted polymer materials as smart chemicals and as drug-delivery systems. (C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 113: 916-921, 2009

引用

页码：916 / 921

页数：6

共 40 条

[1] A wireless, remote query glucose biosensor based on a pH-sensitive polymer [J].