Clear cell sarcoma of the kidney: 3 case reports.

Clear cell sarcoma of the kidney is a distinct, highly malingnant pediatric neoplasm. Its occurrence in adults is extremely rare and the subject of isolated case reports. Material and Methods : We report 3 cases of clear cell sarcoma of the kidney in one men and two women between 23 and 65 years old (mean age is 40 years). A radical nephrectomy with hilar lymph node dissection it-as accomplished. A combination chemotherapy regimen(cisplatin and doxorubicin) was performed on 6 cycles in 1 case. The other 2 case was not underwent chemotherapy or radiation. Results : In the patient underwent the combination chemotherapy, there it-as not evidence of tumor in the abdomen and thorax on CT Scan 4 years later. In one of the two patient not underwent chemotherapy or radiation, the CT scan revealed a left psoas reccurrence three month later; therapy consisted for surgery without chemotherapy or radiation. Four month later tfe CT scan revealed a reccurrence in the left retroperitoneal region and liver and speen metastasis. The patient was dead two month later. The other patient not underwent chemotherapy or radiation was dead seven month after nephrectomy. Conclusion : Optimal treatment is unknown, and surgery, radiotherapy and chemotherapy are used alone but mostly in combination.