Research examining the relationship between acute nicotine use and experimental measures of risk-taking has yielded conflicting results. The present study sought to expand upon research investigating the acute impact of nicotine on risky choice among non-smokers while measuring and controlling for gender, a potentially confounding variable. Utilizing a between-group, double-blind, experimental design, 69 participants were randomly assigned to one of three conditions (placebo, 2 mg, or 4 mg nicotine gum). Participants completed two behavioral risk-taking measures and a motor control task. Individuals in the nicotine conditions demonstrated a main effect of decreased risk-taking on one measure. An interaction between nicotine, gender and risk-taking was found on the second measure of risk-taking, with only males showing decreased risk-taking in higher nicotine conditions. Results suggest nicotine has an acute effect on non-smokers' patterns of risk-taking, and provide direction for further research on differential effects of nicotine on risk-taking tasks.
机构:
Massachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
Massachusetts Gen Hosp, Addict Res Program, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA 02115 USAMassachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
Barr, Ruth S.
Pizzagalli, Diego A.
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Harvard Univ, Dept Psychol, Boston, MA 02115 USAMassachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
Pizzagalli, Diego A.
Culhane, Melissa A.
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机构:
Massachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
Massachusetts Gen Hosp, Addict Res Program, Boston, MA 02114 USAMassachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
Culhane, Melissa A.
Goff, Donald C.
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h-index: 0
机构:
Massachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA 02115 USAMassachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
Goff, Donald C.
Evins, A. Eden
论文数: 0引用数: 0
h-index: 0
机构:
Massachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
Massachusetts Gen Hosp, Addict Res Program, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA 02115 USAMassachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
机构:
Massachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
Massachusetts Gen Hosp, Addict Res Program, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA 02115 USAMassachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
Barr, Ruth S.
Pizzagalli, Diego A.
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Univ, Dept Psychol, Boston, MA 02115 USAMassachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
Pizzagalli, Diego A.
Culhane, Melissa A.
论文数: 0引用数: 0
h-index: 0
机构:
Massachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
Massachusetts Gen Hosp, Addict Res Program, Boston, MA 02114 USAMassachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
Culhane, Melissa A.
Goff, Donald C.
论文数: 0引用数: 0
h-index: 0
机构:
Massachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA 02115 USAMassachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
Goff, Donald C.
Evins, A. Eden
论文数: 0引用数: 0
h-index: 0
机构:
Massachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA
Massachusetts Gen Hosp, Addict Res Program, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA 02115 USAMassachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02114 USA