Genome scan detects quantitative trait loci affecting female fertility traits in Danish and Swedish Holstein cattle

被引:43
作者
Hoglund, J. K. [1 ,2 ,3 ]
Guldbrandtsen, B. [1 ]
Su, G. [1 ]
Thomsen, B. [1 ]
Lund, M. S. [1 ]
机构
[1] Aarhus Univ, Fac Agr Sci, Dept Genet & Biotechnol, DK-8830 Tjele, Denmark
[2] VikingGenetics, S-53221 Skara, Sweden
[3] Sveriges Lantbruksuniv, S-75007 Uppsala, Sweden
关键词
quantitative trait locus; genome-wide scan; female fertility; DAIRY-CATTLE; FUNCTIONAL TRAITS; MILK-PRODUCTION; CALVING TRAITS; CONFORMATION; PARAMETERS; HEALTH; YIELD;
D O I
10.3168/jds.2008-1104
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
Data from the joint Nordic breeding value prediction for Danish and Swedish Holstein grandsire families were used to locate quantitative trait loci (QTL) for female fertility traits in Danish and Swedish Holstein cattle. Up to 36 Holstein grandsires with over 2,000 sons were genotyped for 416 microsatellite markers. Single trait breeding values were used for 12 traits relating to female fertility and female reproductive disorders. Data were analyzed by least squares regression analysis within and across families. Twenty-six QTL were detected on 17 different chromosomes. The best evidence was found for QTL segregating on Bos taurus chromosome (BTA) 1, BTA7, BTA10, and BTA26. On each of these chromosomes, several QTL were detected affecting more than one of the fertility traits investigated in this study. Evidence for segregation of additional QTL on BTA2, BTA9, and BTA24 was found.
引用
收藏
页码:2136 / 2143
页数:8
相关论文
共 23 条
  • [1] ANCKER S, 2006, VIDENSYNTESE REPROD, V113
  • [2] Detection of quantitative trait loci affecting milk production, health, and reproductive traits in Holstein cattle
    Ashwell, MS
    Heyen, DW
    Sonstegard, TS
    Van Tassell, CP
    Da, Y
    VanRaden, PM
    Ron, M
    Weller, JI
    Lewin, HA
    [J]. JOURNAL OF DAIRY SCIENCE, 2004, 87 (02) : 468 - 475
  • [3] Detection of genes influencing economic traits in three French dairy cattle breeds
    Boichard, D
    Grohs, C
    Bourgeois, F
    Cerqueira, F
    Faugeras, R
    Neau, A
    Rupp, R
    Amigues, Y
    Boscher, MY
    Levéziel, H
    [J]. GENETICS SELECTION EVOLUTION, 2003, 35 (01) : 77 - 101
  • [4] CHURCHILL GA, 1994, GENETICS, V138, P963
  • [5] Genetic and phenotypic parameters for 305-day yield, fertility, and survival in Holsteins
    Dematawewa, CMB
    Berger, PJ
    [J]. JOURNAL OF DAIRY SCIENCE, 1998, 81 (10) : 2700 - 2709
  • [6] MAXIMUM LIKELIHOOD FROM INCOMPLETE DATA VIA EM ALGORITHM
    DEMPSTER, AP
    LAIRD, NM
    RUBIN, DB
    [J]. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-METHODOLOGICAL, 1977, 39 (01): : 1 - 38
  • [7] A SIMPLE REGRESSION METHOD FOR MAPPING QUANTITATIVE TRAIT LOCI IN LINE CROSSES USING FLANKING MARKERS
    HALEY, CS
    KNOTT, SA
    [J]. HEREDITY, 1992, 69 : 315 - 324
  • [8] Fine mapping of a quantitative trait locus on chromosome 9 affecting non-return rate in Swedish dairy cattle
    Holmberg, M.
    Sahana, G.
    Andersson-Eklund, L.
    [J]. JOURNAL OF ANIMAL BREEDING AND GENETICS, 2007, 124 (05) : 257 - 263
  • [9] Quantitative trait loci affecting fertility and calving traits in Swedish dairy cattle
    Holmberg, M.
    Andersson-Eklund, L.
    [J]. JOURNAL OF DAIRY SCIENCE, 2006, 89 (09) : 3664 - 3671
  • [10] Estimates of genetic parameters for Canadian Holstein female reproduction traits
    Jamrozik, J
    Fatehi, J
    Kistemaker, GJ
    Schaeffer, LR
    [J]. JOURNAL OF DAIRY SCIENCE, 2005, 88 (06) : 2199 - 2208