Stereoselective synthesis of cis-fused hexahydro-isoindolones

被引:1
作者
Rehn, S [1 ]
Ofial, AR [1 ]
Polborn, K [1 ]
Mayr, H [1 ]
机构
[1] Univ Munich, Dept Chem, Butenandtstr 5-13,Haus F, D-81377 Munich, Germany
关键词
Diels-Alder reactions; isoindolones; lactams; stereoselectivity; x-ray analysis;
D O I
10.3998/ark.5550190.0005.312
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Allylamines, readily accessible by ene reactions of N,N-dibenzyliminium pentachlorostannates with 1,3-enynes, undergo domino reactions with maleic anhydride or maleic imide to give cis-fused hexahydroisoindolones, which were characterized by x-ray analysis.
引用
收藏
页码:120 / 131
页数:12
相关论文
共 24 条
[21]   Domino reactions for library synthesis of small molecules in combinatorial chemistry [J].
Tietze, LF ;
Lieb, ME .
CURRENT OPINION IN CHEMICAL BIOLOGY, 1998, 2 (03) :363-371
[22]   SEQUENTIAL TRANSFORMATIONS IN ORGANIC-CHEMISTRY - A SYNTHETIC STRATEGY WITH A FUTURE [J].
TIETZE, LF ;
BEIFUSS, U .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1993, 32 (02) :131-163
[23]   Domino reactions in organic synthesis [J].
Tietze, LF .
CHEMICAL REVIEWS, 1996, 96 (01) :115-136
[24]   SYNTHESIS OF THE CYTOCHALASIN D ISOINDOLONE UNIT - SOLUTIONS TO THE PROBLEM OF REGIOCHEMISTRY IN N-BENZOYLPYRROLINONE DIELS-ALDER REACTIONS [J].
VEDEJS, E ;
CAMPBELL, JB ;
GADWOOD, RC ;
RODGERS, JD ;
SPEAR, KL ;
WATANABE, Y .
JOURNAL OF ORGANIC CHEMISTRY, 1982, 47 (08) :1534-1546