A novel strategy of structure-guided vaccine design to enhance the availability of immunogens

被引:0
作者
Ratswohl, C. [1 ]
Garcia, C. Vazquez [1 ]
Ahmad, A. U. -W. [1 ]
Lebedin, M. [1 ]
Silvis, C. [1 ]
Spatt, L. [1 ]
Gerhard, C. [1 ]
Olsson, S. [2 ]
de la Rosa, K. [1 ]
机构
[1] Max Delbruck Ctr Mol Med MDC Berlin, Canc & Immunol, Berlin, Germany
[2] Chalmers Univ, Dept Comp Sci & Engn, Gothenburg, Sweden
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
P 027
引用
收藏
页码:173 / 173
页数:1
相关论文
共 50 条
[41]   The transcriptome of Balamuthia mandrillaris trophozoites for structure-guided drug design [J].
Isabelle Q. Phan ;
Christopher A. Rice ;
Justin Craig ;
Rooksana E. Noorai ;
Jacquelyn R. McDonald ;
Sandhya Subramanian ;
Logan Tillery ;
Lynn K. Barrett ;
Vijay Shankar ;
James C. Morris ;
Wesley C. Van Voorhis ;
Dennis E. Kyle ;
Peter J. Myler .
Scientific Reports, 11
[42]   Structure-guided design of β-secretase (BACE-1) inhibitors [J].
McGaughey, Georgia B. ;
Holloway, M. Katharine .
EXPERT OPINION ON DRUG DISCOVERY, 2007, 2 (08) :1129-1138
[43]   Structure-Guided Design of a High Affinity Inhibitor to Human CtBP [J].
Hilbert, Brendan J. ;
Morris, Benjamin L. ;
Ellis, Keith C. ;
Paulsen, Janet L. ;
Schiffer, Celia A. ;
Grossman, Steven R. ;
Royer, William E., Jr. .
ACS CHEMICAL BIOLOGY, 2015, 10 (04) :1118-1127
[44]   Recent applications of protein crystallography and structure-guided drug design [J].
Williams, SP ;
Kuyper, LF ;
Pearce, KH .
CURRENT OPINION IN CHEMICAL BIOLOGY, 2005, 9 (04) :371-380
[45]   Caspases: Structure-Guided Design of Drugs to Control Cell Death [J].
Weber, Irene T. ;
Fang, Bin ;
Agniswamy, Johnson .
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2008, 8 (11) :1154-1162
[46]   Structure-guided insights into potential function of novel genetic variants in the malaria vaccine candidate PfRh5 [J].
Mangou, Khadidiatou ;
Moore, Adam J. ;
Thiam, Laty Gaye ;
Ba, Aboubacar ;
Orfano, Alessandra ;
Desamours, Ife ;
Ndegwa, Duncan Ndungu ;
Goodwin, Justin ;
Guo, Yicheng ;
Sheng, Zizhang ;
Patel, Saurabh D. ;
Diallo, Fatoumata ;
Sene, Seynabou D. ;
Pouye, Mariama N. ;
Faye, Awa Thioub ;
Thiam, Alassane ;
Nunez, Vanessa ;
Diagne, Cheikh Tidiane ;
Sadio, Bacary Djilocalisse ;
Shapiro, Lawrence ;
Faye, Ousmane ;
Mbengue, Alassane ;
Bei, Amy K. .
SCIENTIFIC REPORTS, 2022, 12 (01)
[47]   Accelerating pharmaceutical structure-guided drug design: a successful model [J].
Keefe, Lisa J. ;
Stoll, Vincent S. .
DRUG DISCOVERY TODAY, 2019, 24 (02) :377-381
[48]   Structure-guided design of a selective BCL-XL inhibitor [J].
Lessene, Guillaume ;
Czabotar, Peter E. ;
Sleebs, Brad E. ;
Zobel, Kerry ;
Lowes, Kym N. ;
Adams, Jerry M. ;
Baell, Jonathan B. ;
Colman, Peter M. ;
Deshayes, Kurt ;
Fairbrother, Wayne J. ;
Flygare, John A. ;
Gibbons, Paul ;
Kersten, Wilhelmus J. A. ;
Kulasegaram, Sanji ;
Moss, Rebecca M. ;
Parisot, John P. ;
Smith, Brian J. ;
Street, Ian P. ;
Yang, Hong ;
Huang, David C. S. ;
Watson, Keith G. .
NATURE CHEMICAL BIOLOGY, 2013, 9 (06) :390-+
[49]   The transcriptome of Balamuthia mandrillaris trophozoites for structure-guided drug design [J].
Phan, Isabelle Q. ;
Rice, Christopher A. ;
Craig, Justin ;
Noorai, Rooksana E. ;
McDonald, Jacquelyn R. ;
Subramanian, Sandhya ;
Tillery, Logan ;
Barrett, Lynn K. ;
Shankar, Vijay ;
Morris, James C. ;
Van Voorhis, Wesley C. ;
Kyle, Dennis E. ;
Myler, Peter J. .
SCIENTIFIC REPORTS, 2021, 11 (01)
[50]   Structure-guided design of a selective BCL-XL inhibitor [J].
Lessene G. ;
Czabotar P.E. ;
Sleebs B.E. ;
Zobel K. ;
Lowes K.N. ;
Adams J.M. ;
Baell J.B. ;
Colman P.M. ;
Deshayes K. ;
Fairbrother W.J. ;
Flygare J.A. ;
Gibbons P. ;
Kersten W.J.A. ;
Kulasegaram S. ;
Moss R.M. ;
Parisot J.P. ;
Smith B.J. ;
Street I.P. ;
Yang H. ;
Huang D.C.S. ;
Watson K.G. .
Nature Chemical Biology, 2013, 9 (6) :390-397