Kidney Transplantation in Children

被引:176
作者
Dharnidharka, Vikas R. [1 ,2 ]
Fiorina, Paolo [3 ,4 ,5 ]
Harmon, William E. [3 ,4 ]
机构
[1] Washington Univ, Div Pediat Nephrol, Sch Med, St Louis, MO 63130 USA
[2] St Louis Childrens Hosp, St Louis, MO 63110 USA
[3] Boston Childrens Hosp, Div Nephrol, Boston, MA 02115 USA
[4] Harvard Univ, Sch Med, Boston, MA 02115 USA
[5] Univ Milan, Osped San Raffaele, Ist Ricovero & Cura Carattere Sci, Div Transplant Med, I-20127 Milan, Italy
关键词
PEDIATRIC RENAL-TRANSPLANTATION; POSTTRANSPLANT LYMPHOPROLIFERATIVE DISORDER; COMPLETE STEROID AVOIDANCE; MESENCHYMAL STEM-CELLS; RANDOMIZED-TRIAL; UNITED-STATES; MYCOPHENOLATE-MOFETIL; ORGAN-TRANSPLANTATION; MESSENGER-RNA; RECIPIENTS;
D O I
10.1056/NEJMra1314376
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Transplantation in children with kidney failure once presented many technical, immunologic, and logistic problems that led to worse patient and allograft survival, as compared with adults. Advances in all these areas and the development of pediatric-trial groups have resulted in dramatic improvements, such that young children now have the best long-term graft survival among all age groups, including adults. Copyright © 2014 Massachusetts Medical Society.
引用
收藏
页码:549 / 558
页数:10
相关论文
共 79 条
  • [1] Missed viral surveillance testing visits associate with full blown viral diseases in children receiving kidney transplants
    Al Khasawneh, Eihab
    Araya, Carlos E.
    Dharnidharka, Vikas R.
    [J]. PEDIATRIC TRANSPLANTATION, 2013, 17 (02) : 129 - 132
  • [2] [Anonymous], 2010 ANN TRANSPL REP
  • [3] Adolescent transition to adult care in solid organ transplantation: A consensus conference report
    Bell, L. E.
    Bartosh, S. M.
    Davis, C. L.
    Dobbels, F.
    Al-Uzri, A.
    Lotstein, D.
    Reiss, J.
    Dharnidharka, V. R.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2008, 8 (11) : 2230 - 2242
  • [4] Incidence of BK with tacrolimus versus cyclosporine and impact of preemptive immunosuppression reduction
    Brennan, DC
    Agha, I
    Bohl, DL
    Schnitzler, MA
    Hardinger, HL
    Lockwood, M
    Torrence, S
    Schuessler, R
    Roby, T
    Gaudreault-Keener, M
    Storch, GA
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2005, 5 (03) : 582 - 594
  • [5] Brugnoni D, 1996, IMMUNOL LETT, V52, P61
  • [6] The Clinical Impact of Humoral Immunity in Pediatric Renal Transplantation
    Chaudhuri, Abanti
    Ozawa, Mikki
    Everly, Matthew J.
    Ettenger, Robert
    Dharnidharka, Vikas
    Benfield, Mark
    Mathias, Robert
    Portale, Anthony
    McDonald, Ruth
    Harmon, William
    Kershaw, David
    Vehaskari, V. Matti
    Kamil, Elaine
    Baluarte, H. Jorge
    Warady, Bradley
    Li, Li
    Sigdel, Tara K.
    Hsieh, Szu-chuan
    Dai, Hong
    Naesens, Maarten
    Waskerwitz, Janie
    Salvatierra, Oscar, Jr.
    Terasaki, Paul I.
    Sarwal, Minnie M.
    [J]. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2013, 24 (04): : 655 - 664
  • [7] DEVELOPMENT OF CELL-MEDIATED CYTO-TOXIC IMMUNITY TO RESPIRATORY SYNCYTIAL VIRUS IN HUMAN INFANTS FOLLOWING NATURALLY ACQUIRED INFECTION
    CHIBA, Y
    HIGASHIDATE, Y
    SUGA, K
    HONJO, K
    TSUTSUMI, H
    OGRA, PL
    [J]. JOURNAL OF MEDICAL VIROLOGY, 1989, 28 (03) : 133 - 139
  • [8] Cyclosporin pharmacokinetics in paediatric transplant recipients
    Cooney, GF
    Habucky, K
    Hoppu, K
    [J]. CLINICAL PHARMACOKINETICS, 1997, 32 (06) : 481 - 495
  • [9] Immune Profile of Pediatric Renal Transplant Recipients following Alemtuzumab Induction
    De Serres, Sacha A.
    Mfarrej, Bechara G.
    Magee, Ciara N.
    Benitez, Fanny
    Ashoor, Isa
    Sayegh, Mohamed H.
    Harmon, William E.
    Najafian, Nader
    [J]. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2012, 23 (01): : 174 - 182
  • [10] Improved Survival with Recent Post-Transplant Lymphoproliferative Disorder (PTLD) in Children with Kidney Transplants
    Dharnidharka, V. R.
    Martz, K. L.
    Stablein, D. M.
    Benfield, M. R.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2011, 11 (04) : 751 - 758