First Report of OXA-181-Producing Escherichia coli in China and Characterization of the Isolate Using Whole-Genome Sequencing

被引：88

作者：

Liu, Yanbin ^{[1
,2
]}

Feng, Yu ^{[1
,2
]}

Wu, Wenjing ^{[1
,2
]}

Xie, Yi ^{[3
]}

Wang, Xiaohui ^{[1
,2
]}

Zhang, Xiaoxia ^{[1
,2
]}

Chen, Xinchuan ^{[4
]}

Zong, Zhiyong ^{[1
,2
,5
]}

机构：

[1] Sichuan Univ, West China Hosp, Ctr Infect Dis, Chengdu 610064, Peoples R China

[2] State Key Lab Biotherapy, Div Infect Dis, Chengdu, Peoples R China

[3] Sichuan Univ, West China Hosp, Dept Lab Med, Lab Clin Microbiol, Chengdu 610064, Peoples R China

[4] Sichuan Univ, West China Hosp, Dept Haematol, Chengdu 610064, Peoples R China

[5] Sichuan Univ, West China Hosp, Dept Infect Control, Chengdu 610064, Peoples R China

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2015年 / 59卷 / 08期

关键词：

KLEBSIELLA-PNEUMONIAE; BETA-LACTAMASE; ENTEROBACTERIACEAE; OXA-181; IDENTIFICATION; EMERGENCE; PLASMID; OXA-48; CARBAPENEMASES; BLA(NDM-1);

D O I：

10.1128/AAC.00442-15

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We report the first OXA-181-producing strain in China. bla(OXA-181) was found in sequence type 410 (ST410) Escherichia coli strain WCHEC14828 from a Chinese patient without recent travel history. Genome sequencing and conjugation experiments were performed. bla(OXA-181) was carried on a 51-kb self-transmissible IncX3 plasmid and was linked with qnrS1, a quinolone resistance gene. bla(OXA-181) was introduced onto the IncX3 plasmid from a ColE2-type plasmid, and IncX3 plasmids have the potential to mediate the dissemination of bla(OXA-181).

引用

页码：5022 / 5025

页数：4

共 33 条

[1] Emergence of Klebsiella pneumoniae co-producing NDM-type and OXA-181 carbapenemases [J].

Balm, M. N. D. ;

La, M. -V. ;

Krishnan, P. ;

Jureen, R. ;

Lin, R. T. P. ;

Teo, J. W. P. .

CLINICAL MICROBIOLOGY AND INFECTION, 2013, 19 (09) :E421-E423

[2] SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing [J].

Bankevich, Anton ;

Nurk, Sergey ;

Antipov, Dmitry ;

Gurevich, Alexey A. ;

Dvorkin, Mikhail ;

Kulikov, Alexander S. ;

Lesin, Valery M. ;

Nikolenko, Sergey I. ;

Son Pham ;

Prjibelski, Andrey D. ;

Pyshkin, Alexey V. ;

Sirotkin, Alexander V. ;

Vyahhi, Nikolay ;

Tesler, Glenn ;

Alekseyev, Max A. ;

Pevzner, Pavel A. .

JOURNAL OF COMPUTATIONAL BIOLOGY, 2012, 19 (05) :455-477

[3] Emergence of carbapenem-resistant Klebsiella species possessing the class A carbapenem-hydrolyzing KPC-2 and inhibitor-resistant TEM-30 β-lactamases in New York City [J].

Bradford, PA ;

Bratu, S ;

Urban, C ;

Visalli, M ;

Mariano, N ;

Landman, D ;

Rahal, JJ ;

Brooks, S ;

Cebular, S ;

Quale, J .

CLINICAL INFECTIOUS DISEASES, 2004, 39 (01) :55-60

[4] Emergence of OXA-48 and OXA-181 Carbapenemases among Enterobacteriaceae in South Africa and Evidence of In Vivo Selection of Colistin Resistance as a Consequence of Selective Decontamination of the Gastrointestinal Tract [J].

Brink, Adrian J. ;

Coetzee, Jennifer ;

Corcoran, Craig ;

Clay, Cornelis G. ;

Hari-Makkan, Danusha ;

Jacobson, Rachael K. ;

Richards, Guy A. ;

Feldman, Charles ;

Nutt, Louise ;

van Greune, Johan ;

Deetlefs, J. D. ;

Swart, Karin ;

Devenish, Lesley ;

Poirel, Laurent ;

Nordmann, Patrice .

JOURNAL OF CLINICAL MICROBIOLOGY, 2013, 51 (01) :369-372

[5] Early Dissemination of NDM-1-and OXA-181-Producing Enterobacteriaceae in Indian Hospitals: Report from the SENTRY Antimicrobial Surveillance Program, 2006-2007 [J].

Castanheira, Mariana ;

Deshpande, Lalitagauri M. ;

Mathai, Dilip ;

Bell, Jan M. ;

Jones, Ronald N. ;

Mendes, Rodrigo E. .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2011, 55 (03) :1274-1278

[6] Complete Sequence of a KPC-Producing IncN Multidrug-Resistant Plasmid from an Epidemic Escherichia coli Sequence Type 131 Strain in China [J].

Chen, Liang ;

Hu, Hongyan ;

Chavda, Kalyan D. ;

Zhao, Shulong ;

Liu, Renkun ;

Liang, Hui ;

Zhang, Wei ;

Wang, Xiumei ;

Jacobs, Michael R. ;

Bonomo, Robert A. ;

Kreiswirth, Barry N. .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2014, 58 (04) :2422-2425

[7] KPC-2-encoding plasmids from Escherichia coli and Klebsiella pneumoniae in Taiwan [J].

Chen, Ying-Tsong ;

Lin, Jung-Chung ;

Fung, Chang-Phone ;

Lu, Po-Liang ;

Chuang, Yin-Ching ;

Wu, Tsu-Lan ;

Siu, L. Kristopher .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2014, 69 (03) :628-631

[8] Rapid and simple determination of the Escherichia coli phylogenetic group [J].

Clermont, O ;

Bonacorsi, S ;

Bingen, E .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2000, 66 (10) :4555-4558

[9] Characterization of Enterobacteriaceae producing OXA-48-like carbapenemases in the UK [J].

Dimou, Vassiliki ;

Dhanji, Hiran ;

Pike, Rachel ;

Livermore, David M. ;

Woodford, Neil .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2012, 67 (07) :1660-1665

[10] NDM-1, OXA-48 and OXA-181 carbapenemase-producing Enterobacteriaceae in Sultanate of Oman [J].

Dortet, L. ;

Poirel, L. ;

Al Yaqoubi, F. ;

Nordmann, P. .

CLINICAL MICROBIOLOGY AND INFECTION, 2012, 18 (05) :E144-E148

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