T-Cell Lymphomas, Version 1.2021 Featured Updates to the NCCN Guidelines

被引：29

作者：

Horwitz, Steven M. ^{[1
]}

Ansell, Stephen ^{[2
]}

Ai, Weiyun Z. ^{[3
]}

Barnes, Jeffrey ^{[4
]}

Berta, Stefan K. ^{[5
]}

Clemens, Mark W. ^{[6
]}

Dogan, Ahmet ^{[1
]}

Goodman, Aaron M. ^{[7
]}

Goyal, Gaurav ^{[8
]}

Guitart, Joan ^{[9
]}

Halwani, Ahmad ^{[10
]}

Haverkos, Bradley M. ^{[11
]}

Hoppe, Richard T. ^{[12
]}

Jacobsen, Eric ^{[13
]}

Jagadeesh, Deepa ^{[14
,15
]}

Jones, Allison ^{[16
]}

Kim, Youn H. ^{[12
]}

Mehta-Shah, Neha ^{[17
,18
]}

Olsen, Elise A. ^{[19
]}

Pro, Barbara ^{[9
]}

Rajguru, Saurabh A. ^{[20
]}

Rozati, Sima ^{[21
]}

Said, Jonathan ^{[22
]}

Shaver, Aaron ^{[23
]}

Shustov, Andrei ^{[24
]}

Sokol, Lubomir ^{[25
]}

Torka, Pallawi ^{[26
]}

Torres-Cabala, Carlos ^{[6
]}

Wilcox, Ryan ^{[27
]}

William, Basem M. ^{[28
,29
]}

Zain, Jasmine ^{[30
]}

Dwyer, Mary A. ^{[31
]}

Sundar, Hema ^{[31
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA

[2] Mayo Clin, Canc Ctr, Rochester, MN USA

[3] UCSF Helen Diller Family Comprehens Canc Ctr, San Francisco, CA USA

[4] Massachusetts Gen Hosp, Canc Ctr, Boston, MA 02114 USA

[5] Univ Penn, Abramson Canc Ctr, Philadelphia, PA 19104 USA

[6] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

[7] UC San Diego Moores Canc Ctr, La Jolla, CA USA

[8] ONeal Comprehens Canc Ctr UAB, Birmingham, AL USA

[9] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA

[10] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT USA

[11] Univ Colorado, Canc Ctr, Boulder, CO 80309 USA

[12] Stanford Canc Inst, Stanford, CA USA

[13] Dana Farber Brigham & Womens Canc Ctr, Boston, MA USA

[14] Univ Hosp Seidman Canc Ctr, Case Comprehens Canc Ctr, Cleveland, OH USA

[15] Cleveland Clin, Taussig Canc Inst, Cleveland, OH 44106 USA

[16] Univ Tennessee, Ctr Hlth Sci, St Jude Childrens Res Hosp, Memphis, TN 38163 USA

[17] Barnes Jewish Hosp, Siteman Canc Ctr, St Louis, MO 63110 USA

[18] Washington Univ, Sch Med, St Louis, MO USA

[19] Duke Canc Inst, Durham, NC USA

[20] Univ Wisconsin, Carbone Canc Ctr, Madison, WI USA

[21] Sidney Kimmel Comprehens Canc Ctr Johns Hopkins, Baltimore, MD USA

[22] UCLA, Jonsson Comprehens Canc Ctr, Los Angeles, CA 90024 USA

[23] Vanderbilt Ingram Canc Ctr, Nashville, TN USA

[24] Fred Hutchinson Canc Res Ctr, Seattle Canc Care Alliance, 1124 Columbia St, Seattle, WA 98104 USA

[25] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

[26] Roswell Park Comprehens Canc Ctr, Buffalo, NY USA

[27] Univ Michigan, Rogel Canc Ctr, Ann Arbor, MI 48109 USA

[28] Ohio State Univ, Comprehens Canc Ctr, James Canc Hosp, Columbus, OH 43210 USA

[29] Solove Res Inst, Columbus, OH USA

[30] City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USA

[31] Natl Comprehens Canc Network, Plymouth Meeting, PA USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2020年 / 18卷 / 11期

关键词：

ALPHA INHIBITOR THERAPY; STAT3; MUTATIONS; LYMPHOPROLIFERATIVE DISORDERS; CLINICOPATHOLOGICAL FEATURES; GAMMA/DELTA-LYMPHOMA; ISOCHROMOSOME; 7Q; TRANSPLANTATION; ENTITY; PATHOGENESIS; ABNORMALITY;

D O I：

10.6004/jnccn.2020.0053

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Hepatosplenic T-cell lymphoma (HSTCL) is a rare subtype of T-cell lymphoma associated with an aggressive clinical course and a worse prognosis. HSTCL develops in the setting of chronic immune suppression or immune dysregulation in up to 20% of cases and is most often characterized by spleen, liver, and bone marrow involvement. Diagnosis and management of HSTCL pose significant challenges given the rarity of the disease along with the absence of lymphadenopathy and poor outcome with conventional chemotherapy regimens. These Guidelines Insights focus on the diagnosis and treatment of HSTCL as outlined in the NCCN Guidelines for T-Cell Lymphomas.

引用

页码：1461 / +

页数：11

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