Effect of Thiamine Pyrophosphate on Levels of Serum Lactate, Maximum Oxygen Consumption and Heart Rate in Athletes Performing Aerobic Activity

被引：7

作者：

Bautista-Hernandez, V. M. ^{[1
]}

Lopez-Ascencio, R. ^{[1
]}

Del Toro-Equihua, M. ^{[1
]}

Vasquez, C. ^{[2
]}

机构：

[1] Univ Colima, Fac Med, Colima, Mexico

[2] Univ Colima, Univ Ctr Biomed Invest, Colima, Mexico

来源：

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 2008年 / 36卷 / 06期

关键词：

THIAMINE PYROPHOSPHATE; SERUM LACTATE; MAXIMUM OXYGEN CONSUMPTION; HEAR RATE; AEROBIC ACTIVITY;

D O I：

10.1177/147323000803600608

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The aim of this study was to determine the effect of thiamine pyrophosphate (TPP) on serum lactate levels, maximum oxygen consumption (Vo(2max)) and heart rate in male athletes performing aerobic activity. A double-blind, randomized, crossover study was performed in which lactate levels, Vo2max and heart rates in 27 male athletes were compared at rest and after exercise, following administration of placebo (sodium chloride 0.9%) or TPP (1 mg/kg). At rest, serum lactate levels after placebo or TPP were similar; however, after exercise, the levels were lower in the athletes after taking TPP than after placebo. During exercise, Vo(2max) in athletes on TPP was higher than on placebo. At rest, heart rate after taking placebo or TPP was similar but, after exercise, heart rate was lower after taking TPP than after placebo. It is concluded that TPP caused serum lactate levels and heart rate to be lower than placebo and Vo(2max) to be higher in athletes performing aerobic physical activity.

引用

页码：1220 / 1226

页数：7

共 32 条

[1] Severe lactic acidosis and thiamine administration in an HIV-infected patient on HAART [J].