Endothelial Notch1 in Pulmonary Hypertension Friend or Foe?

被引：17
作者：
Babicheva, Aleksandra
Yuan, Jason X. -J.
机构：
[1] Univ Arizona, Coll Med, Dept Med, Div Translat & Regenerat Med, Tucson, AZ USA
[2] Univ Arizona, Coll Med, Dept Physiol, Tucson, AZ 85724 USA
来源：
CIRCULATION RESEARCH | 2019年 / 124卷 / 02期
基金：
美国国家卫生研究院;
关键词：
BMPR2; Editorials; endothelial dysfunction; Notch1; pulmonary hypertension;
D O I：
10.1161/CIRCRESAHA.118.314496
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：176 / 179
页数：4
相关论文
共 15 条
  • [1] Perspectives on endothelial-to-mesenchymal transition: potential contribution to vascular remodeling in chronic pulmonary hypertension
    Arciniegas, Enrique
    Frid, Maria G.
    Douglas, Ivor S.
    Stenmark, Kurt R.
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2007, 293 (01) : L1 - L8
  • [2] Notch signalling in context
    Bray, Sarah J.
    [J]. NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2016, 17 (11) : 722 - 735
  • [3] Notch1 signalling regulates endothelial proliferation and apoptosis in pulmonary arterial hypertension
    Dabral, Swati
    Tian, Xia
    Kojonazarov, Baktybek
    Savai, Rajkumar
    Ghofrani, Hossein Ardeschir
    Weissmann, Norbert
    Florio, Monica
    Sun, Jan
    Jonigk, Danny
    Maegel, Lavinia
    Grimminger, Friedrich
    Seeger, Werner
    Pullamsetti, Soni Savai
    Schermuly, Ralph Theo
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2016, 48 (04) : 1137 - 1149
  • [4] BMP signaling in vascular biology and dysfunction
    de Vinuesa, Amaya Garcia
    Abdelilah-Seyfried, Salim
    Knaus, Petra
    Zwijsen, An
    Bailly, Sabine
    [J]. CYTOKINE & GROWTH FACTOR REVIEWS, 2016, 27 : 65 - 79
  • [5] TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling
    Hurst, Liam A.
    Dunmore, Benjamin J.
    Long, Lu
    Crosby, Alexi
    Al-Lamki, Rafia
    Deighton, John
    Southwood, Mark
    Yang, Xudong
    Nikolic, Marko Z.
    Herrera, Blanca
    Inman, Gareth J.
    Bradley, John R.
    Rana, Amer A.
    Upton, Paul D.
    Morrell, Nicholas W.
    [J]. NATURE COMMUNICATIONS, 2017, 8
  • [6] The interplay between the cellular hypoxic response and Notch signaling
    Landor, Sebastian K. -J.
    Lendahl, Urban
    [J]. EXPERIMENTAL CELL RESEARCH, 2017, 356 (02) : 146 - 151
  • [7] Notch3 signaling promotes the development of pulmonary arterial hypertension
    Li, Xiaodong
    Zhang, Xiaoxue
    Leathers, Robin
    Makino, Ayako
    Huang, Chengqun
    Parsa, Pouria
    Macias, Jesus
    Yuan, Jason X-J
    Jamieson, Stuart W.
    Thistlethwaite, Patricia A.
    [J]. NATURE MEDICINE, 2009, 15 (11) : 1289 - U89
  • [8] Smooth Muscle Contact Drives Endothelial Regeneration by BMPR2-Notch1-Mediated Metabolic and Epigenetic Changes
    Miyagawa, Kazuya
    Shi, Minyi
    Chen, Pin-I
    Hennigs, Jan K.
    Zhao, Zhixin
    Wang, Mouer
    Li, Caiyun G.
    Saito, Toshie
    Taylor, Shalina
    Sa, Silin
    Cao, Aiqin
    Wang, Lingli
    Snyder, Michael P.
    Rabinovitch, Marlene
    [J]. CIRCULATION RESEARCH, 2019, 124 (02) : 211 - 224
  • [9] Cellular and Molecular Basis of Pulmonary Arterial Hypertension
    Morrell, Nicholas W.
    Adnot, Serge
    Archer, Stephen L.
    Dupuis, Jocelyn
    Jones, Peter Lloyd
    MacLean, Margaret R.
    McMurtry, Ivan F.
    Stenmark, Kurt R.
    Thistlethwaite, Patricia A.
    Weissmann, Norbert
    Yuan, Jason X. -J.
    Weir, E. Kenneth
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 54 (01) : S20 - S31
  • [10] 6-phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia
    Obach, M
    Navarro-Sabaté, A
    Caro, J
    Kong, XG
    Duran, J
    Gómez, M
    Perales, JC
    Ventura, F
    Rosa, JL
    Bartrons, R
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (51) : 53562 - 53570
12