The management of pain in sickle cell disease

被引:35
|
作者
Yaster, M
Kost-Byerly, S
Maxwell, LG
机构
[1] Johns Hopkins Med Inst, Dept Anesthesiol Crit Care Med, Baltimore, MD 21287 USA
[2] Johns Hopkins Med Inst, Dept Pediat, Baltimore, MD 21287 USA
关键词
D O I
10.1016/S0031-3955(05)70233-9
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The pain of vaso-occlusive crisis in sickle cell disease is excruciating, incapacitating, and at times, refractory to even the most advanced analgesic treatments. The authors discuss the pathophysiology of sickle cell disease, define acute and chronic pain syndromes in sickle cell disease, and outline barriers to effective care. A comprehensive, multimodal approach to therapy that includes education, cognitive therapies, anti-inflammatory drugs, opioids, and psychostimulant adjuvant drugs is also provided.
引用
收藏
页码:699 / +
页数:13
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