Early outcomes following lung transplantation in patients aged 65 years and older

被引：7

作者：

Avramenko-Bouvier, A. ^{[1
]}

Weisenburger, G. ^{[2
]}

Jebrak, G. ^{[2
]}

Cerceau, P. ^{[1
]}

Pellenc, Q. ^{[1
,4
]}

Roussel, A. ^{[1
,5
]}

Bunel, V ^{[2
]}

Godet, C. ^{[2
]}

Messika, J. ^{[2
,5
]}

Montravers, P. ^{[3
,5
]}

Castier, Y. ^{[1
,5
]}

Mal, H. ^{[2
,5
]}

Mordant, P. ^{[1
,5
]}

机构：

[1] Univ Paris, Serv Chirurg Vasc Thorac & Transplantat Pulm, Hop Bichat Claude Bernard, AP HP, F-75018 Paris, France

[2] Univ Paris, Serv Pneumol & Transplantat Pulm B, Hop Bichat Claude Bernard, AP HP, F-75018 Paris, France

[3] Univ Paris, Dept Anesthesie Reanimat, Hop Bichat Claude Bernard, AP HP, F-75018 Paris, France

[4] Univ Paris, UFR Diderot, Inserm 1148, F-75018 Paris, France

[5] Univ Paris, UFR Diderot, Inserm 1152, F-75018 Paris, France

来源：

REVUE DES MALADIES RESPIRATOIRES | 2020年 / 37卷 / 10期

关键词：

Lung transplantation; Chronic respiratory failure; Elderly; INTERNATIONAL-SOCIETY; HEART; CANDIDATES; SELECTION; SURVIVAL; COUNCIL; UPDATE;

D O I：

10.1016/j.rmr.2020.08.012

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Introduction. - The number of lung transplantations performed is increasing worldwide. With an improved experience and outcomes, the age of the recipient on its own has ceased to be an absolute contra-indication. We report our first experience with lung transplantation in patients aged 65 years or older. Methods.- From January 2014 to March 2019, the files of patients aged 65 years or older undergoing lung transplantation were retrospectively reviewed. Results. - During the study period, 241 patients underwent lung transplantation in Bichat hospital (Paris, France), including 25 recipients aged 65 years or older. Underlying diagnoses were interstitial (72%) and obstructive (28%) disease. The rate of single lung transplantation was 80%. Sixteen patients required ECMO assistance during the procedure. Early complications were mostly grade III primary graft dysfunction (12%) and cellular rejection (20%). Overall one-year survival rate was 76%. Conclusion. - After a careful selection of the recipients, the early results of our retrospective single center series are encouraging. We continue to consider lung transplantation in rigorously selected recipients of aged 65 years and more. (C) 2020 SPLF. Published by Elsevier Masson SAS. All rights reserved.

引用

页码：769 / 775

页数：7

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