Nano world: A Novel Path for Modern Drug Discovery

被引:1
作者
Ranjan, Nishka [1 ]
Reddy, A. H. Manjunatha [1 ]
机构
[1] RV Coll Engn, Dept Biotechnol, Bangalore 560059, Karnataka, India
来源
MECHANICAL DESIGN AND POWER ENGINEERING, PTS 1 AND 2 | 2014年 / 490-491卷
关键词
PLGA; Polythiophene; IBJT; PEDOT: PSS; Biosensors; Drug Delivery; Nanoparticles; Electroceuticals; NANOPARTICLES;
D O I
10.4028/www.scientific.net/AMM.490-491.123
中图分类号
TH [机械、仪表工业];
学科分类号
0802 ;
摘要
The last two decades have witnessed a plethora of novel biomaterials that work significantly in the discovery of drugs and the point check of drugs, Biosensors. PLGA (Poly-(L-Lactide-co-glycolic Acid)), has already been shown to be a substrate for manufacture of substrates for OFET's, that in the future would be the forefront of electroceuticals. But, Polylactic Acid (PLA) derived and pegylated nanoparticles generated scaffolds, promote neural self differentiation, nanowires derived from Polythiophene(PT's) can be utilised in the area of biosensors. Similarly, PT derived PEDOT:PSS(poly(3,4-ethylenedioxythiophene) poly(styrenesulfonate) polymer doped with appropriate cations is useful to manipulate directly the biological response of cells on the same grounds, organic electrochemical transistors (OECTs)based on PEDOT PSS coupled with bilayer lipid membranes (BLMs) were shown to act as ion-to-electron converters. A solid-state ion bipolar junction transistor (IBJT) has been developed to serve as a circuit element for neurotransmitter signal delivery. Consequently, the traditional drug discovery methods have far gone by. This era demands a much more modified and multiple disciplined methods for modern drug discovery. This review gives an insight and instance of this paradigm.
引用
收藏
页码:123 / 128
页数:6
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