Synthesis, characterization and antibacterial activity of some Schiff bases of 2-amino-3-(N-tolyl carboxamido)-4,5-trimethelene thiophenes

被引:0
作者
Mohan, S
Saravanan, J
机构
[1] MS Ramaiah Coll Pharm, Bangalore 560054, Karnataka, India
[2] MS Ramaiah Coll Pharm, Bangalore 560054, Karnataka, India
关键词
synthesis; characterization; antibacterial activity; Schiff bases;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
2-Amino-3-(N-tolyl carboxamido)-4,5-trimethelene thiophenes (1-III) were synthesized by Gewald reaction. Later, the compounds I-III were treated with ten different substituted aryl aldehydes to yield thirty new Schiff bases (Ia-j to IIIa-j). The compounds were characterized by spectral data and were screened for antibacterial activity. Some of these Schiff bases exhibited promising activity.
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页码:1331 / 1334
页数:4
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