Mesenchymal Stem Cell Therapy for Neurodegenerative Diseases

被引：16
作者：
Chen, Lukui [1 ]
Qiu, Rong [1 ]
Xu, Qiang [2 ]
机构：
[1] Southeast Univ, Zhongda Hosp, Dept Neurosurg, Nanjing 210009, Peoples R China
[2] Guangdong Landau Biotechnol Co Ltd, Guangzhou 510555, Guangdong, Peoples R China
来源：
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | 2014年 / 14卷 / 01期
关键词：
Mesenchymal Stem Cells; Therapy; Neurodegenerative Diseases; AMYOTROPHIC-LATERAL-SCLEROSIS; MARROW STROMAL CELLS; FUNCTIONAL DOPAMINERGIC-NEURONS; AMYLOID-BETA DEPOSITION; HUNTINGTONS-DISEASE; PARKINSONS-DISEASE; RAT MODEL; ALZHEIMERS-DISEASE; NONMOTOR COMPLICATIONS; NEUROTROPHIC FACTOR;
D O I：
10.1166/jnn.2014.9126
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
This paper reviews the recent studies and development of mesenchymal stem cell (MSCs) therapy for neurodegenerative diseases. MSCs transplantation, a promising therapy, can promote functional recovery by producing trophic factors that induce survival and regeneration of host neurons in animal models and patients with neurodegenerative diseases. In this review, we introduce briefly the potential benefits of MSCs. Finally, the possibility of clinical application in neurodegenerative diseases is also discussed.
引用
收藏
页码：969 / 975
页数：7
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