Evaluation of available IgE-binding epitope data and its utility in bioinformatics

被引：40
作者：
Bannon, Gary A.
Ogawa, Tadashi
机构：
[1] Monsanto Co, St Louis, MO 63167 USA
[2] Kansai Univ Welf Sci, Osaka, Japan
来源：
MOLECULAR NUTRITION & FOOD RESEARCH | 2006年 / 50卷 / 07期
关键词：
allergen; crossreactivity; conformational epitope; genetic engineering; linear epitope;
D O I：
10.1002/mnfr.200500276
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
This paper reviews the role played by IgE-binding epitopes in eliciting clinical symptoms, the types of IgE-binding epitopes in allergenic proteins, the methods used to identify IgE-binding epitopes, and the availability of IgE-binding epitopes in allergenic sources. Finally, bioinformatics methods to assess protein allergenicity using knowledge of IgE-binding epitopes are discussed.
引用
收藏
页码：638 / 644
页数：7
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