Synthesis of Derivatives of Cyclopenta[4',5']Pyrido-[3',2':4,5]Thieno[3,2-d]Pyrimidines and Pyrimido[5',4':2,3]-Thieno[2,3-c]Isoquinolines

被引:2
|
作者
Paronikyan, E. G. [1 ]
Dashyan, Sh. Sh. [1 ]
Noravyan, A. S. [1 ]
Minasyan, N. S. [2 ]
机构
[1] Natl Acad Sci Republ Armenia, Sci Technol Ctr Organ & Pharmaceut Chem, AL Mnjoyan Inst Fine Organ Chem, Yerevan 0014, Armenia
[2] Natl Acad Sci Republ Armenia, Sci Technol Ctr Organ & Pharmaceut Chem, Mol Struct Res Inst, Yerevan 0014, Armenia
关键词
alkoxypyrido[2,3-b]thieno[3,2-d]pyrimidines; alkylsulfanylpyrido[2,3-b]thieno[3,2-d]pyrimidines; aminopyrido[2,3-b]thieno[3,2-d]pyrimidines; pyrimidine; condensed systems; BIOLOGICAL EVALUATION; PYRIDO;
D O I
10.1007/s10593-014-1580-6
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Methods have been developed for the preparation of amino, alkoxy, and alkylsulfanyl derivatives of cyclopenta[4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidines and pyrimido[5',4':2,3]thieno[2,3-c]isoquino- lines by the nucleophilic substitution of the 4-chloro derivatives of condensed pyrimidines.
引用
收藏
页码:1188 / 1194
页数:7
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