Recent Clinical Developments of Nanomediated Drug Delivery Systems of Taxanes for the Treatment of Cancer

被引：23

作者：

van Eerden, Ruben A. G. ^{[1
]}

Mathijssen, Ron H. J. ^{[1
]}

Koolen, Stijn L. W. ^{[1
,2
]}

机构：

[1] Erasmus MC Canc Inst, Dept Med Oncol, Rotterdam, Netherlands

[2] Erasmus MC Univ Med Ctr, Dept Hosp Pharm, Rotterdam, Netherlands

来源：

INTERNATIONAL JOURNAL OF NANOMEDICINE | 2020年 / 15卷

关键词：

nanomedicine; nanoparticle; drug delivery systems; taxane; cancer; INCORPORATING MICELLAR NANOPARTICLE; PHASE-II TRIAL; ALBUMIN-BOUND PACLITAXEL; SOLVENT-BASED PACLITAXEL; ADVANCED SOLID TUMORS; CATIONIC LIPOSOMES; CREMOPHOR-FREE; MACROMOLECULAR THERAPEUTICS; ENDOTHELIAL-CELLS; NAB-PACLITAXEL;

D O I：

10.2147/IJN.S272529

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Conventional taxanes are used as cornerstone of the chemotherapeutical treatment for a variety of malignancies. Nevertheless, a large proportion of patients do not benefit from their treatment while they do suffer from severe adverse events related to the solvent or to the active compound. Cremophor EL and polysorbate 80 free formulations, conjugates, oral formulations and different types of drug delivery systems are some examples of the several attempts to improve the treatment with taxanes. In this review article, we discuss recent clinical developments of nanomediated drug delivery systems of taxanes for the treatment of cancer. Targeting mechanisms of drug delivery systems and characteristics of the most commonly used taxane-containing drug delivery systems in the clinical setting will be discussed in this review.

引用

页码：8151 / 8166

页数：16

共 50 条

[1] Recent developments of nanomedicine delivery systems for the treatment of pancreatic cancer
Rezaei, Nastaran
Shahriari, Masoud
Mehrnejad, Faramarz
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2023, 79
[2] Recent developments in liposomal drug delivery systems for the treatment of retinal diseases
Urquhart, Andrew J.
Eriksen, Anne Z.
DRUG DISCOVERY TODAY, 2019, 24 (08) : 1660 - 1668
[3] Microneedles Drug Delivery Systems for Treatment of Cancer: A Recent Update
Seetharam, Aravindram Attiguppe
Choudhry, Hani
Bakhrebah, Muhammed A.
Abdulaal, Wesam H.
Gupta, Maram Suresh
Rizvi, Syed Mohd Danish
Alam, Qamre
Siddaramaiah
Gowda, Devegowda Vishakante
Moin, Afrasim
PHARMACEUTICS, 2020, 12 (11) : 1 - 27
[4] Pulmonary drug delivery systems: Recent developments and prospects
Courrier, HM
Butz, N
Vandamme, TF
CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS, 2002, 19 (4-5): : 425 - 498
[5] Recent Developments in the Study of the Microenvironment of Cancer and Drug Delivery
Chaudhary, Benu
Kumar, Parveen
Arya, Preeti
Singla, Deepak
Kumar, Virender
Kumar, Davinder
Roshan, S.
Wadhwa, Sheetu
Gulati, Monica
Singh, Sachin Kumar
Dua, Kamal
Gupta, Gaurav
Gupta, Madan Mohan
CURRENT DRUG METABOLISM, 2022, 23 (13) : 1027 - 1053
[6] Recent developments in natural and synthetic polymeric drug delivery systems used for the treatment of osteoarthritis
Rahimi, Mahdi
Charmi, Gholamreza
Matyjaszewski, Krzysztof
Banquy, Xavier
Pietrasik, Joanna
ACTA BIOMATERIALIA, 2021, 123 : 31 - 50
[7] Nano-Drug Delivery Systems in Oral Cancer Therapy: Recent Developments and Prospective
Zhang, Yun
Wu, Yongjia
Du, Hongjiang
Li, Zhiyong
Bai, Xiaofeng
Wu, Yange
Li, Huimin
Zhou, Mengqi
Cao, Yifeng
Chen, Xuepeng
PHARMACEUTICS, 2024, 16 (01)
[8] Advancements in utilizing exosomes for cancer therapy through drug delivery systems: recent developments
Karami, Mohammad Hossein
Abdouss, Majid
NANOMEDICINE JOURNAL, 2025, 12 (02) : 181 - 201
[9] Recent developments in novel drug delivery systems for wound healing
Pachuau, Lalduhsanga
EXPERT OPINION ON DRUG DELIVERY, 2015, 12 (12) : 1895 - 1909
[10] Recent Developments in Biopolymeric Nanoparticles for Drug Delivery Systems: An Overview
Barik S.R.
Mohapatra R.K.
Mohapatra P.K.
Mahal A.
El-Ajaily M.M.
Micro and Nanosystems, 2022, 14 (02): : 92 - 100

← 1 2 3 4 5 →