Fabrication of Encapsulated Silicagel Microsphere with Hydroxyapatite for Sustained-release

被引：2
作者：
Yamane, Shihori [1 ]
Yabutsuka, Takeshi [1 ]
Hibino, Mitsuhiro [1 ]
Yao, Takeshi [1 ]
机构：
[1] Kyoto Univ, Grad Sch Energy Sci, Sakyo Ku, Kyoto 6068501, Japan
来源：
BIOCERAMICS 21 | 2009年 / 396-398卷
关键词：
Hydroxyapatite; Apatite Nucleus; Microcapsule; Silicagel; Simulated Body Fluid; Biomimetic method; LOCAL-DELIVERY;
D O I：
10.4028/www.scientific.net/KEM.396-398.519
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Apatite nuclei were precipitated in the pores of silicagel microspheres by raising pH of simulated body fluid (SBF). By a soak in SBF, hydroxyapatite (HAp) was induced from the apatite nuclei and spread over whole surface area of the silicagel microspheres. Then encapsulated silicagel microspheres with HAp were fabricated.
引用
收藏
页码：519 / 522
页数：4
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