Fabrication of Encapsulated Silicagel Microsphere with Hydroxyapatite for Sustained-release

被引：2
作者：
Yamane, Shihori [1 ]
Yabutsuka, Takeshi [1 ]
Hibino, Mitsuhiro [1 ]
Yao, Takeshi [1 ]
机构：
[1] Kyoto Univ, Grad Sch Energy Sci, Sakyo Ku, Kyoto 6068501, Japan
来源：
BIOCERAMICS 21 | 2009年 / 396-398卷
关键词：
Hydroxyapatite; Apatite Nucleus; Microcapsule; Silicagel; Simulated Body Fluid; Biomimetic method; LOCAL-DELIVERY;
D O I：
10.4028/www.scientific.net/KEM.396-398.519
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Apatite nuclei were precipitated in the pores of silicagel microspheres by raising pH of simulated body fluid (SBF). By a soak in SBF, hydroxyapatite (HAp) was induced from the apatite nuclei and spread over whole surface area of the silicagel microspheres. Then encapsulated silicagel microspheres with HAp were fabricated.
引用
收藏
页码：519 / 522
页数：4
相关论文
共 50 条
  • [31] Fabrication and dissolution behavior of hollow hydroxyapatite microspheres intended for controlled drug release
    Sun, Ruixue
    Chen, Kezheng
    Lu, Yupeng
    MATERIALS RESEARCH BULLETIN, 2009, 44 (10) : 1939 - 1942
  • [32] Adsorption and Sustained Release of Insulin from Zinc Hydroxyapatite Microparticle with Poly (Lactic acid) Coating
    Tonegawa, T.
    Ikoma, T.
    Yoshioka, T.
    Shinozaki, K.
    Hanagata, N.
    Tanaka, J.
    BIOCERAMICS 21, 2009, 396-398 : 507 - 510
  • [33] Sustained release of adriamycin from implanted hydroxyapatite blocks for the treatment of experimental osteogenic sarcoma in mice
    Itokazu, M
    Kumazawa, S
    Wada, E
    Wenyi, Y
    CANCER LETTERS, 1996, 107 (01) : 11 - 18
  • [34] A curcumin sustained-release hydrogel prepared from Pickering emulsions stabilized by modified amorphous calcium phosphate nanoparticles
    Cai, Jindian
    Guo, Yong
    Liang, Yaodong
    He, Yongjun
    COLLOID AND POLYMER SCIENCE, 2024, 302 (05) : 781 - 790
  • [35] Controllable fabrication of hollow TiO2 spheres as sustained release drug carrier
    Liu, Di
    Bi, Yong-guang
    ADVANCED POWDER TECHNOLOGY, 2019, 30 (10) : 2169 - 2177
  • [36] In vitro evaluation of sustained ciprofloxacin release from κ-carrageenan-crosslinked chitosan/hydroxyapatite hydrogel nanocomposites
    Mandavinia, Gholam Reza
    Karimi, Mohammad Hasan
    Soltaniniya, Mina
    Massoumi, Bakshali
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 126 : 443 - 453
  • [37] Hydroxyapatite-biopolymers-ZnO composite with sustained Ceftriaxone release as a drainage system for treatment of purulent cavities
    Sukhodub, Liudmyla B.
    Kumeda, Mariia
    Bielai, Volodymyr
    Sukhodub, Leonid F.
    CARBOHYDRATE POLYMERS, 2021, 266
  • [38] Nonstoichiometric hydroxyapatite-anionic collagen composite as support for the double sustained release of gentamicin and norfloxacin/ciprofloxacin
    Martins, VCA
    Goissis, G
    ARTIFICIAL ORGANS, 2000, 24 (03) : 224 - 230
  • [39] Novel method for the fabrication of multiscale structure collagen/hydroxyapatite-microsphere composites based on CaCO3 microparticle templates
    Wei, Qingrong
    Lu, Jian
    Ai, Hua
    Jiang, Bo
    MATERIALS LETTERS, 2012, 80 : 91 - 94
  • [40] Construction and Characterization of a Novel Sustained-Release Delivery System for Hydrophobic Pesticides Using Biodegradable Polydopamine-Based Microcapsules
    Zou, Aihua
    Yang, Ying
    Cheng, Jiagao
    Garamus, Vasil M.
    Li, Na
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018, 66 (25) : 6262 - 6268
12345