Short-term outcome of patients with ST-segment elevation myocardial infarction (STEMI) treated with an everolimus-eluting bioresorbable vascular scaffold

被引:46
作者
Wiebe, Jens [1 ]
Moellmann, Helge [2 ]
Most, Astrid [1 ]
Doerr, Oliver [1 ]
Weipert, Kay [1 ]
Rixe, Johannes [1 ]
Liebetrau, Christoph [1 ,2 ]
Elsaesser, Albrecht [3 ]
Achenbach, Stephan [4 ]
Hamm, Christian [1 ,2 ]
Nef, Holger [1 ]
机构
[1] Univ Giessen, Dept Cardiol, Med Klin 1, D-35392 Giessen, Germany
[2] Kerckhoff Heart & Thorax Ctr, Dept Cardiol, D-61231 Bad Nauheim, Germany
[3] Klinikum Oldenburg, Dept Cardiol, D-26133 Oldenburg, Germany
[4] Univ Erlangen Nurnberg, Dept Cardiol, Med Klin 2, D-91054 Erlangen, Germany
关键词
STEMI; ST-segment elevation myocardial infarction; Bioresorbable vascular scaffold; Percutaneous coronary intervention; ACUTE CORONARY SYNDROMES; REPERFUSION THERAPY; PROGNOSTIC VALUE; BARE-METAL; STENTS; CLOPIDOGREL; MORTALITY; EUROPE; IMPACT; 2ND-GENERATION;
D O I
10.1007/s00392-013-0630-x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
To evaluate safety and efficacy of the everolimus-eluting bioresorbable scaffold (BVS) in patients with ST-segment elevation myocardial infarction (STEMI). According to the current guidelines, drug-eluting stents are the treatment of choice in patients with STEMI. BVS represents a new technology capable to restore the native vessel vasomotion and potentially avoiding long-term limitations such as stent thrombosis. From October 2012 to May 2013, patients with evidence of STEMI eligible for BVS implantation were included in this study. Exclusion criteria were not defined. A total of 25 patients, respectively 31 lesions, were treated. Procedural success was achieved in 97 %. Two major adverse cardiac events occurred during hospitalization and follow-up: one patient with cardiogenic shock at the index procedure subsequently died. One patient suffered from instable angina with need for interventional revascularization of a previously untreated vessel. One target vessel failure as a consequence of an intra-procedural dissection was seen. However, no target lesion failure was noted. During 132.7 +/- A 68.7 days of follow-up none of the patients died. Our findings suggest that implantation of BVS in STEMI patients is feasible in this small cohort of highly selected patients. Further evaluation in randomized-controlled trials is needed.
引用
收藏
页码:141 / 148
页数:8
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