ISCR2, Another Vehicle for blaVEB Gene Acquisition

被引：33

作者：

Poirel, Laurent ^{[1
,2
]}

Mugnier, Pauline D. ^{[1
,2
]}

Toleman, Mark A. ^{[3
]}

Walsh, Timothy R. ^{[3
]}

Rapoport, Melina J. ^{[4
]}

Petroni, Alejandro ^{[4
]}

Nordmann, Patrice ^{[1
,2
]}

机构：

[1] Hop Bicetre, Fac Med Paris Sud, INSERM,Serv Bacteriol Virol, APHP,Emerging Resistance Antibiot U914, F-94275 Le Kremlin Bicetre, France

[2] Univ Paris Sud, F-94275 Le Kremlin Bicetre, France

[3] Cardiff Univ, Sch Med, Dept Med Microbiol, Cardiff, Wales

[4] Inst Nacl Enfermedades Infecciosas ANLIS Dr Carlo, Dept Bacteriol, Serv Antimicrobianos, Buenos Aires, DF, Argentina

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2009年 / 53卷 / 11期

关键词：

SPECTRUM BETA-LACTAMASE; MEDIATED QUINOLONE RESISTANCE; ACINETOBACTER-BAUMANNII; ANTIBIOTIC-RESISTANCE; PSEUDOMONAS-AERUGINOSA; ESCHERICHIA-COLI; MOLECULAR ANALYSIS; CLASS-1; INTEGRON; VIBRIO-CHOLERAE; ELEMENTS;

D O I：

10.1128/AAC.00414-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The expanded-spectrum beta-lactamase (ESBL) gene bla(VEB-1), identified worldwide in Enterobacteriaceae and Pseudomonas aeruginosa, is associated with either class 1 integrons or repeated elements. We report here the first association of bla(VEB-1a) with the insertion sequence ISCR2 in six Acinetobacter species isolates recovered from Argentina. That genetic structure was likely at the origin of the mobilization of this ESBL gene.

引用

收藏

页码：4940 / 4943

页数：4

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