Novel synthesis of a tetra-substituted imidazole P38 MAP Kinase inhibitor and development of routes to a 2,4-disubstituted pyridine.

被引：0

作者：

Marcantonio, KM ^{[1
]}

Frey, LF ^{[1
]}

Frantz, D ^{[1
]}

Murry, J ^{[1
]}

Soheili, A ^{[1
]}

Tillyer, R ^{[1
]}

Grabowski, EJJ ^{[1
]}

Reider, P ^{[1
]}

机构：

[1] Merck & Co Inc, Merck Res Labs, Proc Res, Rahway, NJ 07065 USA

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2002年 / 224卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

740-ORGN

引用

页码：U234 / U234

页数：1

共 30 条

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[2] Development of a Practical Synthesis of a Pyrazolopyridinone-Based p38 MAP Kinase Inhibitor
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[3] Design, synthesis and biological evaluations of novel substituted imidazooxazoles as potent p38 MAP kinase inhibitors
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ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 230 : U2723 - U2723
[4] Evaluation of chiral purity for a substituted imidazole p38 MAP kinase inhibitor and its intermediates using a single chiral capillary electrophoresis method
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[5] Synthesis, In Silico Studies, and In Vitro Anti-Inflammatory Activity of Novel Imidazole Derivatives Targeting p38 MAP Kinase
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[6] 4-aryl-5-heteroaryl-2-thio-substituted imidazoles: Approach to p38 MAP kinase inhibitor prodrugs
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[7] SAR of 2,6-diamino-3,5-difluoropyridinyl substituted heterocycles as novel p38 MAP kinase inhibitors
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[8] MEDI 198-A high throughput, automated chemistry approach to the lead optimization of novel P38 MAP kinase inhibitors derived from 1,4-disubstituted naphthalenes
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[9] Structure active relationship of substituted imidazo(2,1-b)thiazoles:: Novel, selective p38 MAP kinase inhibitors
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[10] Towards the improvement of the synthesis of novel 4(5)-aryl-5(4)-heteroaryl-2-thio-substituted imidazoles and their p38 MAP kinase inhibitory activity
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