A return to work program improves parasympathetic activity and psychiatric symptoms in workers on sick leave due to depression

被引：6

作者：

Hattori, Saki ^{[1
]}

Kishida, Ikuko ^{[1
,2
]}

Suda, Akira ^{[1
]}

Kawanishi, Chiaki ^{[3
]}

Miyauchi, Masatoshi ^{[1
]}

Shiraishi, Yohko ^{[1
]}

Fujibayashi, Mami ^{[4
]}

Tsujita, Natsuki ^{[5
]}

Ishii, Chie ^{[2
]}

Moritani, Toshio ^{[6
]}

Saigusa, Yusuke ^{[7
]}

Hirayasu, Yoshio ^{[1
,8
]}

机构：

[1] Yokohama City Univ, Sch Med, Dept Psychiat, Kanazawa Ku, 3-9 Fukuura, Yokohama, Kanagawa 2360004, Japan

[2] Fujisawa Hosp, 383 Kotuka, Fujisawa, Kanagawa 2518530, Japan

[3] Sapporo Med Univ, Grad Sch Med, Dept Neuropsychiaty, Chuo Ku, S-1,W-16, Sapporo, Hokkaido 0608543, Japan

[4] Setsunan Univ, Div Phys & Hlth Educ, 17-8 Ikedanakamachi, Neyagawa, Osaka 5728508, Japan

[5] Kyoto Univ, Grad Sch Human & Environm Studies, Sakyo Ku, Yoshidanihonmatsucho, Kyoto 6068316, Japan

[6] Kyoto Sangyo Univ, Fac Gen Educ, Kita Ku, Kyoto 6068555, Japan

[7] Yokohama City Univ, Sch Med, Dept Biostat, Kanazawa Ku, 3-9 Fukuura, Yokohama, Kanagawa 2360004, Japan

[8] Hirayasu Hosp, 346 Kyozuka, Urasoe, Okinawa 9012553, Japan

来源：

HELIYON | 2019年 / 5卷 / 07期

基金：

日本学术振兴会;

关键词：

Psychiatry; Depression; Return to work program; Autonomic nervous system; Workers on sick leave; Heart rate variability; HEART-RATE-VARIABILITY; NERVOUS-SYSTEM ACTIVITY; MENTAL-DISORDERS; TO-WORK; ABSENCE; JAPANESE; HEALTH; THERAPY; MARKER;

D O I：

10.1016/j.heliyon.2019.e02151

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Background: People with depression have autonomic function disturbances. In Japan, workers who take leave due to depression often undergo a work-focused intervention program called the return to work (RTW) program at a mental health hospital during their leave of absence. However, its biological efficacy remains unclear. We investigated the biological efficacy of the RTW program, including changes in autonomic nervous system (ANS) activity, in workers on sick leave due to depression in Japan. Methods: The study involved 104 workers on sick leave due to major depressive disorder or bipolar disorder who underwent the RTW program for 3 months in Yokohama City University Hospital. The ANS activity of all patients was evaluated using heart rate variability at the beginning and end of the 3-month RTW program. Psychiatric symptoms were evaluated using the Montgomery-Asberg Depression Rating Scale-Japanese (MADRS-J) and Social Adaptation Self-evaluation Scale (SASS). We followed up 3 months after the end of the program and investigated the association between the success in returning to work within 3 months after the end of the RTW program and several factors, including ANS activity, depressive symptoms, and demographic factors. Results: Parasympathetic activity was significantly higher and depressive symptom severity was significantly lower at program end than at baseline. Logistic regression analysis showed that the change in depressive symptoms was significantly associated with success in returning to work. Conclusion: We suggest that the RTW program improves parasympathetic activity as well as psychiatric symptoms. ANS activity was not a predictor of a successful return to work within 3 months after the end of the program in workers on sick leave due to depression, but further studies with a larger sample size are needed.

引用

页数：5

共 31 条

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