Osteosarcopenia: a risk factor for osteoporotic fractures

被引:0
作者
Mastaglia, Silvina [1 ]
机构
[1] Univ Buenos Aires, UBA CONICET Hosp Clin, Inst Inmunol Genet & Metab INIGEM, Invest Consejo Invest Cient & Tecn CONICET, RA-1053 Buenos Aires, DF, Argentina
来源
ACTA BIOQUIMICA CLINICA LATINOAMERICANA | 2016年 / 50卷 / 03期
关键词
osteosarcopenia; osteoporosis; fractures; VITAMIN-D STATUS; SKELETAL-MUSCLE; HIP-FRACTURE; CALCIUM SUPPLEMENTATION; PHYSICAL PERFORMANCE; PROTEIN INTAKE; BODY SWAY; BONE LOSS; SARCOPENIA; EXPRESSION;
D O I
暂无
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Age-related sarcopenia is a condition which typically shows a decline in muscle mass and strength due to multifactorial causes. Bones and muscles are two interrelated tissues. The mechanical forces applied on bones are those derived from muscle contraction, conditioning bone properties, such as mass, size, shape and architecture. Therefore, the decline of muscle mass and strength would lead to a decrease in bone quality and quantity resulting in bone frailty. For this reason, sarcopenia is a condition that increases the risk of suffering falls and fractures in older adults. Currently, osteosarcopenia is the term used to identify those older adults with a greater risk of fractures due to bone frailty; however, a consensus of the medical community is needed for developing diagnostic criteria which makes it possible to identify patients with a high risk of developing osteoporotic fractures, to perform adequate therapeutic interventions and to improve the quality of life of older adults.
引用
收藏
页码:357 / 365
页数:9
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