A new method of [99mTc]-ciprofloxacin preparation and quality control

被引：12

作者：

Rodriguez-Puig, Daniel

Piera, Carlos

Fuster, David

Soriano, Alex

Sierra, Jose Maria

Rubi, Sebastia

Suades, Joan

机构：

[1] Hosp Clin Barcelona, CDIC, Nucl Med Serv, Radiopharmacol Unit, E-08036 Barcelona, Spain

[2] Inst Invest Biomed August Pi Sunyer, E-08036 Barcelona, Spain

[3] Hosp Clin Barcelona, Dept Infect Dis, E-08036 Barcelona, Spain

[4] Hosp Clin Barcelona, Micro Dept, E-08036 Barcelona, Spain

来源：

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS | 2006年 / 49卷 / 13期

关键词：

technetium-99m; ciprofloxacin; prosthesis infection; quality control;

D O I：

10.1002/jlcr.1134

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

[Tc-99m]-ciprofloxacin is a useful radiopharmaceutical for the detection of osteoarticular prosthesis infection. We report a new preparation method based on the use of tartrate anion as an exchange ligand and tartaric acid as a source of tartrate. An improved quality control procedure is also reported that allows measuring the level of [Tc-99m]-tartrate present in the radiopharmaceutical preparation. Copyright (c) 2006 John Wiley & Sons, Ltd.

引用

页码：1171 / 1176

页数：6

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