Epitranscriptomics of Mammalian Mitochondrial Ribosomal RNA

被引：10

作者：

Laptev, Ivan ^{[1
]}

Dontsova, Olga ^{[1
,2
,3
,4
]}

Sergiev, Petr ^{[1
,2
,3
,5
]}

机构：

[1] Lomonosov Moscow State Univ, Belozersky Inst Phys Chem Biol, Moscow 119992, Russia

[2] Skolkovo Inst Sci & Technol, Ctr Life Sci, Skolkovo 143028, Moscow Region, Russia

[3] Lomonosov Moscow State Univ, Dept Chem, Moscow 119992, Russia

[4] Shemyakin Ovchinnikov Inst Bioorgan Chem, Moscow 117997, Russia

[5] Lomonosov Moscow State Univ, Inst Funct Genom, Moscow 119992, Russia

来源：

CELLS | 2020年 / 9卷 / 10期

基金：

俄罗斯科学基金会;

关键词：

mitochondria; ribosome; translation; RNA modification; ribosome assembly; INITIATION-FACTOR; 3; ESCHERICHIA-COLI; LARGE SUBUNIT; PSEUDOURIDINE SYNTHASE; POSTTRANSCRIPTIONAL MODIFICATIONS; M(1)A58 METHYLTRANSFERASE; SACCHAROMYCES-CEREVISIAE; KASUGAMYCIN RESISTANCE; PROTEIN COMPLEX; BASE-PAIR;

D O I：

10.3390/cells9102181

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Modified nucleotides are present in all ribosomal RNA molecules. Mitochondrial ribosomes are unique to have a set of methylated residues that includes universally conserved ones, those that could be found either in bacterial or in archaeal/eukaryotic cytosolic ribosomes and those that are present exclusively in mitochondria. A single pseudouridine within the mt-rRNA is located in the peptidyltransferase center at a position similar to that in bacteria. After recent completion of the list of enzymes responsible for the modification of mammalian mitochondrial rRNA it became possible to summarize an evolutionary history, functional role of mt-rRNA modification enzymes and an interplay of the mt-rRNA modification and mitoribosome assembly process, which is a goal of this review.

引用

页数：21

共 50 条

[21] Current Views of the Structure of the Mammalian Mitochondrial Ribosome
Koc, Emine C.
Haque, Md. Emdadul
Spremulli, Linda L.
ISRAEL JOURNAL OF CHEMISTRY, 2010, 50 (01) : 45 - 59
[22] The mammalian mitochondrial epitranscriptome
Rebelo-Guiomar, Pedro
Powell, Christopher A.
Van Haute, Lindsey
Minczuk, Michal
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, 2019, 1862 (03): : 429 - 446
[23] Global Epitranscriptomics Profiling of RNA Post-Transcriptional Modifications as an Effective Tool for Investigating the Epitranscriptomics of Stress Response
Rose, Rebecca E.
Pazos, Manuel A., II
Curcio, M. Joan
Fabris, Daniele
MOLECULAR & CELLULAR PROTEOMICS, 2016, 15 (03) : 932 - 944
[24] Mitochondrial small ribosomal RNA is a component of germinal granules in Xenopus embryos
Kashikawa, M
Amikura, R
Kobayashi, S
MECHANISMS OF DEVELOPMENT, 2001, 101 (1-2) : 71 - 77
[25] Mitochondrial protein synthesis: Figuring the fundamentals, complexities and complications, of mammalian mitochondrial translation
Lightowlers, Robert N.
Rozanska, Agata
Chrzanowska-Lightowlers, Zofia M.
FEBS LETTERS, 2014, 588 (15) : 2496 - 2503
[26] Editorial: Computational Epitranscriptomics: Bioinformatic Approaches for the Analysis of RNA Modifications
Dassi, Erik
Baranov, Pavel V.
Pelizzola, Mattia
FRONTIERS IN GENETICS, 2020, 11
[27] Stabilization of Ribosomal RNA of the Small Subunit by Spermidine in Staphylococcus aureus
Belinite, Margarita
Khusainov, Iskander
Soufari, Heddy
Marzi, Stefano
Romby, Pascale
Yusupov, Marat
Hashem, Yaser
FRONTIERS IN MOLECULAR BIOSCIENCES, 2021, 8
[28] In vitro integration of ribosomal RNA synthesis, ribosome assembly, and translation
Jewett, Michael C.
Fritz, Brian R.
Timmerman, Laura E.
Church, George M.
MOLECULAR SYSTEMS BIOLOGY, 2013, 9
[29] Function of Plant DExD/H-Box RNA Helicases Associated with Ribosomal RNA Biogenesis
Liu, Yuelin
Imai, Ryozo
FRONTIERS IN PLANT SCIENCE, 2018, 9
[30] Reconstructing the evolution of the mitochondrial ribosomal proteome
Smits, Paulien
Smeitink, Jan A. M.
van den Heuvel, Lambert P.
Huynen, Martijn A.
Ettema, Thijs J. G.
NUCLEIC ACIDS RESEARCH, 2007, 35 (14) : 4686 - 4703

← 1 2 3 4 5 →