Hypersensitivity reactions to carboplatin in children

被引：27

作者：

Lazzareschi, I ^{[1
]}

Ruggiero, A ^{[1
]}

Riccardi, R ^{[1
]}

Attinà, G ^{[1
]}

Colosimo, C ^{[1
]}

Lasorella, A ^{[1
]}

机构：

[1] Catholic Univ Rome, Div Pediat Oncol, I-00168 Rome, Italy

来源：

JOURNAL OF NEURO-ONCOLOGY | 2002年 / 58卷 / 01期

关键词：

carboplatin; hypersensitivity; children; desensitization;

D O I：

10.1023/A:1015853200090

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Hypersensitivity reactions to carboplatin are rare but sometimes life-threatening events may occur requiring discontinuation of treatment. In our study, we describe clinical features and diagnostic procedures of carboplatin-associated reactions in children affected by low-grade astrocytoma and treated with multiple courses of carboplatin. In 6 out of 29 children, we reported allergic events. We also report a desensitization protocol for carboplatin administration, which allowed the patients to receive effective treatment without adverse reactions.

引用

页码：33 / 37

页数：5

共 21 条

[1] CARBOPLATIN AND RECURRENT CHILDHOOD BRAIN-TUMORS [J].

ALLEN, JC ;

WALKER, R ;

LUKS, E ;

JENNINGS, M ;

BARFOOT, S ;

TAN, C .

JOURNAL OF CLINICAL ONCOLOGY, 1987, 5 (03) :459-463

[2]

Broome CB, 1996, MED PEDIATR ONCOL, V26, P105

[3]

CHANG SM, 1995, CANCER, V75, P1171, DOI 10.1002/1097-0142(19950301)75:5<1171::AID-CNCR2820750518>3.0.CO

[4]

2-F

[5] IMMEDIATE (TYPE-I) ALLERGIC RESPONSES TO PLATINUM COMPOUNDS [J].

CLEARE, MJ ;

HUGHES, EG ;

JACOBY, B ;

PEPYS, J .

CLINICAL ALLERGY, 1976, 6 (02) :183-195

[6] SPECIFIC IGE ANTIBODIES TO PLATINUM SALTS IN SENSITIZED WORKERS [J].

CROMWELL, O ;

PEPYS, J ;

PARISH, WE ;

HUGHES, EG .

CLINICAL ALLERGY, 1979, 9 (02) :109-117

[7] RESPIRATORY ALLERGY CAUSED BY PLATINUM SALTS [J].

FREEDMAN, SO ;

KRUPEY, J .

JOURNAL OF ALLERGY, 1968, 42 (04) :233-&

[8] HIT-LGG: Therapy protocol for the treatment of children with low-grade glioma - Interim report. [J].

Gnekow, AK ;

Kaatsch, P ;

Kortmann, R ;

Wiestler, OD .

KLINISCHE PADIATRIE, 2000, 212 (04) :177-184

[9] A modified, prolonged desensitization protocol in carboplatin allergy [J].

Goldberg, A ;

ConfinoCohen, R ;

Fishman, A ;

Beyth, Y ;

Altaras, M .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1996, 98 (04) :841-843

[10] CARBOPLATIN AND VINCRISTINE FOR RECURRENT AND NEWLY DIAGNOSED LOW-GRADE GLIOMAS OF CHILDHOOD [J].

PACKER, RJ ;

LANGE, B ;

ATER, J ;

NICHOLSON, HS ;

ALLEN, J ;

WALKER, R ;

PRADOS, M ;

JAKACKI, R ;

REAMAN, G ;

NEEDLES, MN ;

PHILLIPS, PC ;

RYAN, J ;

BOYETT, JM ;

GEYER, R ;

FINLAY, J .

JOURNAL OF CLINICAL ONCOLOGY, 1993, 11 (05) :850-856

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