Palladium(II)-Catalyzed Oxidative Arylation of Quinoxalin-2(1H)-ones with Arylboronic Acids

被引：175

作者：

Carrer, Amandine ^{[1
]}

Brion, Jean-Daniel ^{[1
]}

Messaoudi, Samir ^{[1
]}

Alami, Mouad ^{[1
]}

机构：

[1] Univ Paris 11, CNRS, BioCIS UMR 8076, LabEx LERMIT,Lab Chim Therapeut,Fac Pharm, F-92296 Chatenay Malabry, France

来源：

ORGANIC LETTERS | 2013年 / 15卷 / 21期

关键词：

C-H FUNCTIONALIZATION; CATALYZED DIRECT ARYLATION; COUPLING REACTIONS; SITE-SELECTIVITY; BOND ARYLATIONS; HALOGENATION; ENAMINONES; ACCESS; FACILE;

D O I：

10.1021/ol4028946

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A straightforward palladium-catalyzed oxidative C-3 arylation of quinoxalin-2(1H)-ones with arylboronic acids is reported. This protocol is compatible with a wide range of functional groups and allows construction of various biologically important quinoxalin-2(1H)-one backbones.

引用

收藏

页码：5606 / 5609

页数：4

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