Boronic acid ester with dopamine as a tool for bioconjugation and for visualization of cell apoptosis

被引：25

作者：

Scarano, Wei ^{[1
]}

Lu, Hongxu ^{[1
]}

Stenzel, Martina H. ^{[1
]}

机构：

[1] Univ New S Wales, Sch Chem, Ctr Adv Macromol Design, Sydney, NSW, Australia

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 48期

关键词：

OVARIAN-CANCER; COMPLEX; RAFT; ACTIVATION; PEROXIDE; DELIVERY; PH;

D O I：

10.1039/c3cc49100e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Boronic esters are investigated as a pathway to conjugate biological molecules to polymers. Although the stability of the boronic ester was slightly dependent on the molecular weight of the polymer and the pH value, the conjugates were stable when micelles were endocytosed by cells. Only the onset of apoptosis led to cleavage of the boronic ester.

引用

页码：6390 / 6393

页数：4

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