Elemental sulfur accelerated the reactivity of the 3-position of indole for the construction of chromeno[2,3-b]indoles

被引：19

作者：

Liu, Jianming ^{[1
]}

Yan, Xuyang ^{[1
]}

Liu, Na ^{[1
]}

Zhang, Yanyan ^{[1
]}

Zhao, Shufang ^{[1
]}

Wang, Xiaopei ^{[1
]}

Zhuo, Kelei ^{[1
]}

Yue, Yuanyuan ^{[1
]}

机构：

[1] Henan Normal Univ, Henan Key Lab Boron Chem & Adv Energy Mat, Collaborat Innovat Ctr Henan Prov Green Mfg Fine, Key Lab Green Chem Media & React,Minist Educ,Sch, Xinxiang 453007, Henan, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2018年 / 5卷 / 06期

基金：

中国博士后科学基金; 中国国家自然科学基金;

关键词：

WILLGERODT-KINDLER REACTIONS; C-H FUNCTIONALIZATION; METAL-FREE CONDITIONS; ALKYNES; SALICYLALDEHYDES; DERIVATIVES; CYCLIZATION; ACTIVATION; SULFIDE; CYCLOADDITION;

D O I：

10.1039/c7qo01114h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An intermolecular cross-cyclization between salicylaldehydes and indoles for the preparation of chromeno[2,3-b]indole derivatives was successfully developed by using elemental sulfur as the promoter and oxidant. Various chromeno[2,3-b]indoles can be prepared using indoles and salicylaldehydes bearing different functional groups. The preliminary mechanistic investigations demonstrated that elemental sulfur not only acted as an additional oxidant but also facilitated the reactivity of the 3-position of indole.

引用

页码：1034 / 1038

页数：5

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