Copper-Catalyzed Direct Oxidative C-H Functionalization of Unactivated Cycloalkanes into Cycloalkyl Benzo[b]phosphole Oxides

被引：40
|
作者：
Ma, Dumei [1 ]
Pan, Jiaoting [2 ,3 ]
Yin, Lu [1 ]
Xu, Pengxiang [2 ,3 ]
Gao, Yuxing [2 ,3 ]
Yin, Yingwu [1 ]
Zhao, Yufen [2 ,3 ]
机构：
[1] Xiamen Univ, Coll Chem & Chem Engn, Dept Chem & Biochem Engn, Xiamen 361005, Fujian, Peoples R China
[2] Xiamen Univ, Coll Chem & Chem Engn, Dept Chem, Xiamen 361005, Fujian, Peoples R China
[3] Xiamen Univ, Coll Chem & Chem Engn, Key Lab Chem Biol Fujian Prov, Xiamen 361005, Fujian, Peoples R China
来源：
ORGANIC LETTERS | 2018年 / 20卷 / 12期
关键词：
SIMPLE ALKANES; PHOTOPHYSICAL PROPERTIES; C(SP(3))-H BOND; METAL-FREE; BENZOPHOSPHOLE OXIDES; MEDIATED CYCLIZATION; ORGANIC ELECTRONICS; CASCADE CYCLIZATION; PI-SYSTEMS; AMINATION;
D O I：
10.1021/acs.orglett.8b01108
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The first simple and efficient Cu-catalyzed radical addition/cyclization of various unactivated cycloalkanes with diaryl(arylethynyl)-phosphine oxides has been developed, providing a general, one-step approach to construct a new class of important benzo[b]phosphole oxides via sequential C-H functionalization along with two new C-C bond formations.
引用
收藏
页码：3455 / 3459
页数：5
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