Taming the clot-buster tPA

被引：5

作者：

Dawson, Ted M.

Dawson, Valina L.

机构：

[1] Johns Hopkins Univ, Sch Med, Inst Cell Engn, Baltimore, MD 21205 USA

[2] Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21205 USA

[3] Johns Hopkins Univ, Sch Med, Dept Neurosci, Baltimore, MD 21205 USA

[4] Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21205 USA

[5] Johns Hopkins Univ, Sch Med, Dept Neurosci, Baltimore, MD 21205 USA

[6] Johns Hopkins Univ, Sch Med, Dept Physiol, Baltimore, MD 21205 USA

来源：

NATURE MEDICINE | 2006年 / 12卷 / 09期

关键词：

D O I：

10.1038/nm0906-993

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Treating stroke with tissue plasminogen activator (tPA) can help dissolve blood clots and improve outcome. But tPA also increases the risk of hemorrhage and has other deleterious effects. A new approach to treatment minimizes these negative effects.

引用

页码：993 / 994

页数：2

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