Current indications to parathyroidectomy in CKD patients before and after renal transplantation

被引：10

作者：

Messa, Piergiorgio ^{[1
]}

Regalia, Anna ^{[1
]}

Alfieri, Carlo Maria ^{[1
]}

Cresseri, Donata ^{[1
]}

Forzenigo, Laura ^{[2
]}

Gandolfo, Maria Teresa ^{[1
]}

Rastaldi, Maria Pia ^{[3
,4
]}

机构：

[1] Fdn IRCCS Ca Granda, Osped Maggiore Policlin, Unit Nephrol Dialysis & Renal Transplant, Dept Med & Med Specialties, I-20122 Milan, Italy

[2] Fdn IRCCS Ca Granda, Osped Maggiore Policlin, Radiol Unit, I-20122 Milan, Italy

[3] Fdn IRCCS Ca Granda, Osped Maggiore Policlin, Res Lab Nephrol, I-20122 Milan, Italy

[4] Fdn G DAmico, Milan, Italy

来源：

JOURNAL OF NEPHROLOGY | 2013年 / 26卷 / 06期

关键词：

Cinacalcet; Hypercalcemia; Parathyroidectomy; Renal transplant; Secondary hyperparathyroidism; CALCIUM-SENSING RECEPTOR; CHRONIC KIDNEY-DISEASE; CINACALCET HCL; VITAMIN-D; HYPERCALCEMIC HYPERPARATHYROIDISM; PERSISTENT HYPERPARATHYROIDISM; SECONDARY HYPERPARATHYROIDISM; GRAFT DYSFUNCTION; RISK-FACTOR; RECIPIENTS;

D O I：

10.5301/jn.5000277

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Secondary hyperparathyroidism (SHP) is one of the most challenging complications in the most advanced stages of end-stage renal disease. In the last decade, newly available medical tools have greatly increased the possibilities for controlling SHP. However, one of these tools, cinacalcet, has not yet been approved for its use in transplanted patients and the evidence for its safety in this clinical setting is still incomplete. For these reasons, many questions still remain open for the clinical nephrologist: when to consider a parathyroidectomy (PTX) in a patient on a waiting list for kidney transplant (KTx); when to recommend PTX after KTx; when could a regression of parathyroid hyperplasia be expected at any time after KTx. In the present paper, we will briefly deal with these questions in the light of an unusual clinical case.

引用

页码：1025 / 1032

页数：8

共 39 条

[1] Calcium-sensing receptor regulation of renal mineral ion transport [J].