Deoxygenative Borylation of Secondary and Tertiary Alcohols

被引：162

作者：

Friese, Florian W. ^{[1
]}

Studer, Armido ^{[1
]}

机构：

[1] Westfalische Wilhelms Univ, Inst Organ Chem, Corrensstr 40, D-48149 Munster, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2019年 / 58卷 / 28期

基金：

欧洲研究理事会;

关键词：

alcohols; borylation; deoxygenation; photoredox catalysis; radical reactions; COPPER-CATALYZED BORYLATION; CROSS-COUPLING REACTIONS; ALKYL-HALIDES; RADICAL DEOXYGENATION; ALKYLBORONIC ESTERS; SUBSTITUTION; ALLENYL;

D O I：

10.1002/anie.201904028

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two different approaches for the deoxygenative radical borylation of secondary and tertiary alcohols are presented. These transformations either proceed through a metal-free silyl-radical-mediated pathway or utilize visible-light photoredox catalysis. Readily available xanthates or methyl oxalates are used as radical precursors. The reactions show broad substrate scope and high functional-group tolerance, and are conducted under mild and practical conditions.

引用

页码：9561 / 9564

页数：4

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