PMMA/PHEA Interpenetrating Network Embedded With Iron Oxide Nanoparticles for Drug Delivery Applications

被引：3
作者：
Kiran, Kalpana [1 ]
Goswami, Sudipta [1 ]
机构：
[1] Birla Inst Technol, Dept Chem Engn & Technol, Ranchi 835215, Jharkhand, India
来源：
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS | 2014年 / 63卷 / 18期
关键词：
Crosslink density; differential scanning calorimetry; drug diffusion; interpenetrating polymer networks; iron oxide nanoparticles; SILVER NANOPARTICLES; POLYMER; RELEASE; HYDROGEL; CHITOSAN; BEHAVIOR; MATRIX; IPNS; GUM;
D O I：
10.1080/00914037.2014.886235
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
Semi-interpenetrating polymer networks (IPNs) are prepared from poly methyl methacrylate and 2-hydroxy ethyl acrylate networks with the presence of super-paramagnetic ferric oxide nanoparticles (<30 nm) through free radical polymerization. PMMA/PHEA semi-IPNs having blend ratio 60:40, 50:50, 40:60 (wt/wt) are characterized with respect to swelling, crosslink density, FTIR, DSC, TGA, SEM, and drug loading and drug release properties. Bactericidal effect on IPNs is checked by cell growth study of E. coli.
引用
收藏
页码：963 / 970
页数：8
相关论文
共 49 条
  • [31] Physico-mechanical, thermal and morphological behaviour of polyurethane/poly(methyl methacrylate) semi-interpenetrating polymer networks
    Kumar, H
    Kumar, AA
    Siddaramaiah
    [J]. POLYMER DEGRADATION AND STABILITY, 2006, 91 (05) : 1097 - 1104
  • [32] Prediction of Hildebrand Solubility Parameters of Acrylate and Methacrylate Monomers and Their Mixtures by Molecular Simulation
    Lewin, John L.
    Maerzke, Katie A.
    Schultz, Nathan E.
    Ross, Richard B.
    Siepmann, J. Ilja
    [J]. JOURNAL OF APPLIED POLYMER SCIENCE, 2010, 116 (01) : 1 - 9
  • [33] Li SJ, 2006, J PHARM PHARM SCI, V9, P238
  • [34] Hydrogel networks as nanoreactors: A novel approach to silver nanoparticles for antibacterial applications
    Mohan, Y. Murah
    Lee, Kyungjae
    Premkumar, Thathan
    Geckeler, Kurt E.
    [J]. POLYMER, 2007, 48 (01) : 158 - 164
  • [35] First successful design of semi-IPN hydrogel-silver nanocomposites: A facile approach for antibacterial application
    Murthy, P. S. K.
    Mohan, Y. Murah
    Varaprasad, K.
    Sreedhar, B.
    Raju, K. Mohana
    [J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2008, 318 (02) : 217 - 224
  • [36] Application of Hybrid Organic/Inorganic Dendritic ABA Type Triblock Copolymers as New Nanocarriers in Drug Delivery Systems
    Namazi, Hassan
    Jafarirad, Saeed
    [J]. INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS, 2011, 60 (09) : 603 - 619
  • [37] Preparation of a Magnetic-Field-Sensitive Hydrogel and Preliminary Study of Its Drug Release Behavior
    Namdeo, Mini
    Bajpai, S. K.
    Kakkar, S.
    [J]. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 2009, 20 (12) : 1747 - 1761
  • [38] Mathematical models describing polymer dissolution: consequences for drug delivery
    Narasimhan, B
    [J]. ADVANCED DRUG DELIVERY REVIEWS, 2001, 48 (2-3) : 195 - 210
  • [39] Qiu Y., 2003, AAPS PHARMSCITECH, V4, P406, DOI [10.1208/pt040451, DOI 10.1208/PT040451]
  • [40] RITGER P L, 1987, Journal of Controlled Release, V5, P37, DOI 10.1016/0168-3659(87)90035-6
12345