PMMA/PHEA Interpenetrating Network Embedded With Iron Oxide Nanoparticles for Drug Delivery Applications

被引:3
作者
Kiran, Kalpana [1 ]
Goswami, Sudipta [1 ]
机构
[1] Birla Inst Technol, Dept Chem Engn & Technol, Ranchi 835215, Jharkhand, India
关键词
Crosslink density; differential scanning calorimetry; drug diffusion; interpenetrating polymer networks; iron oxide nanoparticles; SILVER NANOPARTICLES; POLYMER; RELEASE; HYDROGEL; CHITOSAN; BEHAVIOR; MATRIX; IPNS; GUM;
D O I
10.1080/00914037.2014.886235
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Semi-interpenetrating polymer networks (IPNs) are prepared from poly methyl methacrylate and 2-hydroxy ethyl acrylate networks with the presence of super-paramagnetic ferric oxide nanoparticles (<30 nm) through free radical polymerization. PMMA/PHEA semi-IPNs having blend ratio 60:40, 50:50, 40:60 (wt/wt) are characterized with respect to swelling, crosslink density, FTIR, DSC, TGA, SEM, and drug loading and drug release properties. Bactericidal effect on IPNs is checked by cell growth study of E. coli.
引用
收藏
页码:963 / 970
页数:8
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