MALT lymphoma in children: A report from the NHL-BFM study group

被引:29
作者
Claviez, Alexander
Meyer, Ulrike
Dominick, Christoph
Beck, James F.
Rister, Manfred
Tiemann, Markus
机构
[1] Univ Kiel, Dept Pediat, Childrens Hosp, D-25105 Kiel, Germany
[2] Univ Giessen, Dept Pediat, NHL BFM Study Ctr, Giessen, Germany
[3] St Annastiftskrankenhaus Ludwigshafen, Dept Pediat, Ludwigshafen, Germany
[4] Ernst Moritz Arndt Univ Greifswald, Dept Pediat, Greifswald, Germany
[5] Kemperhof Klinikum, Dept Pediat, Koblenz, Germany
[6] Univ Kiel, Dept Hematopathol, Kiel, Germany
关键词
children; extranodal involvement; MALT lymphoma; marginal zone lymphoma;
D O I
10.1002/pbc.20575
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Marginal zone lymphomas of MALT type comprise a considerable group of indolent B-cell non-Hodgkin lymphoma (NHL) in adult patients. In childhood, however, these tumors are extremely rare, as nearly all pediatric patients have aggressive NHL. Among 2,703 children and adolescents registered into the prospective multicenter NHL-BFM treatment studies since 1986, only 4 patients (0.1%) displayed features of MALT lymphoma. These tumors were localized in the stomach, breast, lower lid, and conjunctiva, respectively and they were associated with H. pylori infection in two patients. All children are alive but long-term follow-up will be mandatory to assess the behavior of MALT lymphoma in this age group.
引用
收藏
页码:210 / 214
页数:5
相关论文
共 34 条
[1]   Regression of salivary gland MALT lymphoma after treatment for Helicobacter pylori [J].
Alkan, S ;
Karcher, DS ;
Newman, MA ;
Cohen, P .
LANCET, 1996, 348 (9022) :268-269
[2]  
[Anonymous], PEDIAT HEMATOPATHOLO
[3]   Extragastric mucosa-associated lymphoid tissue lymphoma showing the regression by Helicobacter pylori eradication therapy [J].
Arima, N ;
Tsudo, M .
BRITISH JOURNAL OF HAEMATOLOGY, 2003, 120 (05) :790-792
[4]   New approach to classifying non-hodgkin's lymphomas: Clinical features of the major histologic subtypes [J].
Armitage, JO ;
Weisenburger, DD .
JOURNAL OF CLINICAL ONCOLOGY, 1998, 16 (08) :2780-2795
[5]   MALT lymphoma of labial minor salivary gland in an immunocompetent child with a gastric Helicobacter pylori infection [J].
Berrebi, D ;
Lescoeur, B ;
Faye, A ;
Faure, C ;
Vilmer, E ;
Peuchmaur, M .
JOURNAL OF PEDIATRICS, 1998, 133 (02) :290-292
[6]   Consecutive regression of concurrent laryngeal and gastric MALT lymphoma after anti-Helicobacter pylori therapy [J].
Caletti, G ;
Togliani, T ;
Fusaroli, P ;
Sabattini, E ;
Khodadadian, E ;
Gamberi, B ;
Gobbi, M ;
Pileri, S .
GASTROENTEROLOGY, 2003, 124 (02) :537-543
[7]   PREVENTION AND TREATMENT OF LOW-GRADE B-CELL PRIMARY GASTRIC LYMPHOMA BY ANTI-H-PYLORI THERAPY [J].
CAMMAROTA, G ;
TURSI, A ;
MONTALTO, M ;
PAPA, A ;
BRANCA, G ;
VECCHIO, FM ;
RENZI, C ;
VERZI, A ;
ARMUZZI, A ;
PRETOLANI, S ;
FEDELI, G ;
GASBARRINI, G .
JOURNAL OF CLINICAL GASTROENTEROLOGY, 1995, 21 (02) :118-122
[8]   The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas [J].
Dierlamm, J ;
Baens, M ;
Wlodarska, I ;
Stefanova-Ouzounova, M ;
Hernandez, JM ;
Hossfeld, DK ;
De Wolf-Peeters, C ;
Hagemeijer, A ;
Van den Berghe, H ;
Marynen, P .
BLOOD, 1999, 93 (11) :3601-3609
[9]  
ElenitobaJohnson KSJ, 1997, AM J CLIN PATHOL, V107, P92
[10]   Long term outcome of patients with gastric marginal zone B cell lymphoma of mucosa associated lymphoid tissue (MALT) following exclusive Helicobacter pylori eradication therapy:: experience from a large prospective series [J].
Fischbach, W ;
Goebeler-Kolve, ME ;
Dragosics, B ;
Greiner, A ;
Stolte, M .
GUT, 2004, 53 (01) :34-37