Allosteric activation of the CaR by L-amino acids

被引:19
作者
Kobilka, B [1 ]
机构
[1] Stanford Univ, Sch Med, Howard Hughes Med Inst, Dept Mol & Cellular Physiol, Stanford, CA 94305 USA
[2] Stanford Univ, Sch Med, Div Cardiovasc Med, Stanford, CA 94305 USA
关键词
D O I
10.1073/pnas.97.9.4419
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:4419 / 4420
页数:2
相关论文
共 18 条
  • [1] Dimerization of the extracellular calcium-sensing receptor (CaR) on the cell surface of CaR-transfected HEK293 cells
    Bai, M
    Trivedi, S
    Brown, EM
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (36) : 23605 - 23610
  • [2] CERESA BP, 1994, J BIOL CHEM, V269, P29557
  • [3] L-Amino acid sensing by the extracellular Ca2+-sensing receptor
    Conigrave, AD
    Quinn, SJ
    Brown, EM
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (09) : 4814 - 4819
  • [4] Switching of the coupling of the beta(2)-adrenergic receptor to different G proteins by protein kinase A
    Daaka, Y
    Luttrell, LM
    Lefkowitz, RJ
    [J]. NATURE, 1997, 390 (6655) : 88 - 91
  • [5] Sporadic hypoparathyroidism caused by de novo gain-of-function mutations of the Ca2+-sensing receptor
    DeLuca, F
    Ray, K
    Mancilla, EE
    Fan, GF
    Winer, KK
    Gore, P
    Spiegel, AM
    Baron, J
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1997, 82 (08) : 2710 - 2715
  • [6] Agonists induce conformational changes in transmembrane domains III and VI of the beta(2) adrenoceptor
    Gether, U
    Lin, S
    Ghanouni, P
    Ballesteros, JA
    Weinstein, H
    Kobilka, BK
    [J]. EMBO JOURNAL, 1997, 16 (22) : 6737 - 6747
  • [7] Heptahelical receptor signaling: Beyond the G protein paradigm
    Hall, RA
    Premont, RT
    Lefkowitz, RJ
    [J]. JOURNAL OF CELL BIOLOGY, 1999, 145 (05) : 927 - 932
  • [8] G protein-coupled receptors I. Diversity of receptor-ligand interactions
    Ji, TH
    Grossmann, M
    Ji, IH
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (28) : 17299 - 17302
  • [9] GABAB receptors function as a heteromeric assembly of the subunits GABABR1 and GABABR2
    Jones, KA
    Borowsky, B
    Tamm, JA
    Craig, DA
    Durkin, MM
    Dai, M
    Yao, WJ
    Johnson, M
    Gunwaldsen, C
    Huang, LY
    Tang, C
    Shen, QR
    Salon, JA
    Morse, K
    Laz, T
    Smith, KE
    Nagarathnam, D
    Noble, SA
    Branchek, TA
    Gerald, C
    [J]. NATURE, 1998, 396 (6712) : 674 - 679
  • [10] GABAB-receptor subtypes assemble into functional heteromeric complexes
    Kaupmann, K
    Malitschek, B
    Schuler, V
    Heid, J
    Froest, W
    Beck, P
    Mosbacher, J
    Bischoff, S
    Kulik, A
    Shigemoto, R
    Karschin, A
    Bettler, B
    [J]. NATURE, 1998, 396 (6712) : 683 - 687