Pegylated liposomal doxorubicin plus highly active antiretroviral therapy versus highly active antiretroviral therapy alone in HIV patients with Kaposi's sarcoma

被引:71
作者
Martín-Carbonero, L
Barrios, A
Saballs, P
Sirera, G
Santos, J
Palacios, R
Valencia, ME
Alegre, M
Podzamczer, D
González-Lahoz, J
机构
[1] Hosp Carlos III, Inst Salud Carlos III, Madrid, Spain
[2] Hosp del Mar, Barcelona, Spain
[3] Hosp Badalona Germans Trias & Pujol, Barcelona, Spain
[4] Hosp Univ Virgen Victoria, Malaga, Spain
[5] Hosp Sant Pau, Barcelona, Spain
[6] Hosp Univ Bellvitge, Barcelona, Spain
关键词
D O I
10.1097/01.aids.0000131385.60974.b9
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Twenty-eight HIV patients either naive or failing highly active antiretroviral therapy (HAART) with moderate-advanced Kaposi's sarcoma (KS) were randomly chosen to initiate a new HAART regimen plus pegylated liposomal doxorubicin (PLD) or the new HAART regimen alone. After 48 weeks, better response rates were observed in the HAART plus PLD group (76% versus 20%). In HIV-infected patients with moderate-advanced KS, HAART alone may not be enough for KS response.
引用
收藏
页码:1737 / 1740
页数:4
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