Understanding parathyroid hormone action

被引：23
作者：
Partridge, Nicola C. [1 ]
Li, Xin [1 ]
Qin, Ling [1 ]
机构：
[1] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Dept Physiol & Biophys, Piscataway, NJ 08854 USA
来源：
SKELETAL DEVELOPMENT AND REMODELING IN HEALTH, DISEASE, AND AGING | 2006年 / 1068卷
关键词：
parathyroid hormone; PTH; EGF; amphiregulin; bone resorption; bone formation; osteoblast; MCP-1;
D O I：
10.1196/annals.1346.024
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
In addition to regulating serum calcium and stimulating bone resorption, parathyroid hormone (PTH) is known to stimulate bone formation under certain conditions. The mechanisms behind this counterintuitive anabolic action are largely unknown. We have set out to identify PTH-regulated genes that might be responsible for each of these contrasting effects of the hormone. This article describes our work on a select number of those genes.
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页码：187 / 193
页数：7
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