Optimal Support of Wound Healing: New Insights

被引:107
作者
Baron, Jens Malte [1 ]
Glatz, Martin [2 ]
Proksch, Ehrhardt [3 ]
机构
[1] Rhein Westfal TH Aachen, Dept Dermatol & Allergol, Pauwelsstr 30, DE-52074 Aachen, Germany
[2] Univ Hosp Zurich, Dept Dermatol, Zurich, Switzerland
[3] Univ Kiel, Dept Dermatol, Kiel, Germany
关键词
Wound healing; Dexpanthenol; Minor wounds; Healing; GROWTH-FACTOR-BETA; HYPERTROPHIC SCARS; STRATUM-CORNEUM; SKIN; FIBROBLASTS; DEXPANTHENOL; KELOIDS; PROLIFERATION; PROTEIN; METALLOPROTEINASES;
D O I
10.1159/000505291
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background: The ultimate goal of wound healing following minor injury is to form a tissue regenerate that has functionality and visual appearance as close to the original skin as possible. The body's physiological response to any wound is traditionally characterised by three distinct steps: inflammation, proliferation and remodelling. Summary: New insights suggest that the three phases overlap (and even occur in parallel) in both time and space in the wound, necessitating a clinical approach that targets each stage simultaneously to ensure rapid repair and wound closure without further complications. Ingredients that exhibit activity across each of the three phases, such as dexpanthenol, are of value in the context of minor wound care and scar management. Key Messages: In addition to treatment and ingredient selection, it is also important to consider broader clinical best practices and self-care options that can be used to optimise the management of minor wounds. An individualised approach that can account for a patient's unique requirements and preferences is critical in achieving effective wound recovery.
引用
收藏
页码:593 / 600
页数:8
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